HEALTH SCIENCES > MEDICINE > HATTER INSTITUTE FOR CARDIOLOGY RESEARCH

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Research Output

Authored books

Mayosi, B.M., Dhai, A., Folb, P.I., Gevers, W., Hussey, G.D., Kirkman, M., Madela-Mtla, E.N., Moja, L., Moodley, J., Ncayiyana, D., Pick, W., Siegfried, N. and Volmink, J. 2010.Revitalising Clinical Reseach in South Africa: A Study on Clinical Research and Related Training in South Africa. Pretoria, South Africa: Academy of Science South Africa. 255pp. ISBN 9780981415956. [IIDMM]

Chapters in books

Allard, D. and Meintjes, G. 2010. HIV and trauma. In A. Nicol and E. Steyn (eds), Handbook of Trauma, pp. 374-380. Second Edition. South Africa: Oxford University Press Southern Africa (Pty) Ltd. ISBN 9780195987478.

Benatar, S.R. 2009. Ethics and tropical diseases: some global considerations. In G.C. Cook and A.I. Zumla (eds), Manson's Tropical Diseases, pp. 83-91. Twenty-second edition. India: Saunders Elsevier. ISBN 9781416039884.

Hussey, G.D., Hawkridge, T. and Hanekom, W.A. 2009. Tuberculosis vaccines. In H.S. Schaaf and A.I. Zumla (eds), Tuberculosis: A Comprehensive Clinical Reference, pp. 107-116. Europe: Elsevier Inc. ISBN 9781416039884. [IIDMM]

Levitt, N.S., Ross, I.L. and Dave, J.A. 2010. Basic endocrine concepts in health and critical illness. In M.F.M. James (ed.), Anaesthesia for Patients with Endocrine Disease, pp. 1-14. Oxford: Oxford University Press. ISBN 9780199570256.

Maartens, G. 2010. Prevention of opportunistic infections in adults. In S.S. Abdool Karim and Q. Abdool Karim (eds), HIV/AIDS in South Africa, pp. 479-488. Second Edition. Cape Town: Cambridge University Press. ISBN 9780521147934.

Mody, G.M. and Mayosi, B.M. 2010. Acute rheumatic fever. In Rheumatology, pp. 1029-2063. 5th Edition. Philadelphia, PA: Mosby Elsevier. ISBN 9780323065511.

Nachega, J. and Maartens, G. 2009. Clinical aspects of tuberculosis HIV-infected adults. In H.S. Schaaf and A.I. Zumla (eds), Tuberculosis: A Comprehensive Clinical Reference, pp. 524-531. Europe: Elsevier Inc. ISBN 9781416039884.

Potter, P.C. 2010. Sublingual immunotherapy in allergic rhinitis and asthma. In R. Pawankar, S.T. Holgate and L.J. Rosenwasser (eds), Allergy Frontiers: Therapy and Prevention, pp. 217-226. Volume 5. New York: Springer. ISBN 9784431993612.

Potter, P.C. and Buys, C. 2010. Investigating the allergic patient. In R.J. Green, C. Motala and P.C. Potter (eds), ALLSA Handbook of Practical Allergy, pp. 13-29. Third Edition. South Africa: Allergy Society of South Africa. ISBN 9780620480864.

van Rooyen, C., Matthee, P. and Potter, P.C. 2010. The immuno-solid-phase allergen chip (ISAC). In R.J. Green, C. Motala and P.C. Potter (eds), ALLSA Handbook of Practical Allergy, pp. 454-458. Third Edition. South Africa: Allergy Society of South Africa. ISBN 9780620480864.

Wilson, D. and Fairall, L. 2010. Challenges in managing AIDS in South Africa. In S.S. Abdool Karim and Q. Abdool Karim (eds), HIV/AIDS in South Africa, pp. 503-528. Second. Cape Town: Cambridge University Press. ISBN 9780521147934.

Wood, R. 2010. Antiretroviral therapy. In S.S. Abdool Karim and Q. Abdool Karim (eds), HIV/AIDS in South Africa, pp. 529-550. Second Edition. Cape Town: Cambridge University Press. ISBN 9780521147934. [IIDMM]

Articles in peer-reviewed Journals

Abel, B., Tameris, M.D., Mansoor, N., Gelderbloem, S., Hughes, J., Abrahams, D.A., Makhethe, L., Erasmus, M., de Kock, M., Van der Merwe, L., Hawkridge, A., Veldsman, A., Hatherill, M., Schirru, G., Pau, M., Hendricks, J., Weverling, G., Goudsmit, J., Sizemore, D., McClain, J., Goetz, M.A., Gearhart, J., Mahomed, H., Hussey, G.D., Sadoff, J.C. andHanekom, W.A. 2010. The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults. American Journal of Respiratory and Critical Care Medicine, 181: 1407-1417. [IIDMM]

Adam, T., Opie, L.H. and Essop, M.F. 2010. AMPK activation represses the human gene promoter of the cardiac isoform of acetyl-CoA carboxylase: role of nuclear respiratory factor-1. Biochemical and Biophysical Research Communications, 398: 495-499.

Allie, N., Keeton, R., Court, N., Abel, B., Fick, L., Vasseur, V., Vacher, R., Olleros, M., Drutskaya, M.S., Guler, R., Nedospasov, S., Garcia, I., Ryffel, B., Quesniaux, V. andJacobs, M. 2010. Limited role for lymphotoxin  in the host immune response to Mycobacterium tuberculosis. Journal of Immunology, 185: 4292-4301. [IIDMM]

Arendse, R. and Irusen, E. 2009. An atropine and glycopyrrolate combination reduces mortality in organophosphate poisoning. Human & Experimental Toxicology, 28(11): 715-720.

Arendse, R., Gcelu, A., Scott, C., Beighton, P. and Kalla, A.A. 2010. Do the radiographic features of joint destruction in tophaceous gout imply a different pathophysiology to that of rheumatoid and psoriatic arthritis? Clinical Rheumatology, 29: 1181-1183.

Arendse, C., Wearne, N., Okpechi, I.G. and Swanepoel, C.R. 2010. The acute, the chronic and the news of HIV-related renal disease in Africa. KidneyInternational, 78: 239-245.

Asselman, V., Thienemann, F., Pepper, D.J., Boulle, A.M., Wilkinson, R.J., Meintjes, G.and Marais, S. 2010. Central nervous system disorders afrer starting antiretroviral therapy in South Africa. AIDS, 24(18): 2871-2876. [IIDMM]

Autran, B., Asturias, E.J., Evans, S., Harrigan-Go, K., Hussey, G.D., John, T.J., Lambert, P.-H., Law, L., Midthun, K., Nohynek, H., Salmaso, S., Smith, P.G., Zuber, P.L.F.,Bentsi-Enchill, A., Caric, A., Pfeifer, D., Duclos, P. and Wood, D. 2009. Global safety of vaccines: strengthening systems for monitoring, management and the role of GACVS. Expert Review of Vaccines, 8(6): 705-716. [IIDMM]

Ayodele, O.E.A., Okpechi, I. and Swanepoel, C.R. 2010. Predictors of poor renal outcome in patients with biopsy-proven lupus nephritis. Nephrology, 15: 482-490.

Bachmann, M.O., Fairall, L., Lombard, C., Timmerman, V., van der Merwe, S., Bateman, E.D. and Zwarenstein, M. 2010. Effect on tuberculosis outcomes of educational outreach to South African clinics during two randomised trials. InternationalJournal of Tuberculosis and Lung Disease, 14(3): 311-317.

Bateman, E.D., Reddel, H.K., Eriksson, G., Peterson, S., Ostlund, O., Sears, M.R., Jenkins, C., Humbert, M., Buhl, R., Harrison, T.M., Quirce, S. and O'Byrne, P.M. 2010. Overall asthma control: the relationship between current control and future risk. Journal of Allergy and Clinical Immunology, 125: 600-608.

Bateman, E.D., Tashkin, D., Siafakas, N., Dahl, R., Towse, L., Massey, D., Pavia, D. andZhong, N. 2010. A one-year trial of tiotropium Respimat (R) plus usual therapy in COPD patients. Respiratory Medicine, 104: 1460-1472.

Bekker, L. and Wood, R. 2010. Community-based management of multidrug-resistant tuberculosis in South Africa (Editorial). International Journal of Tuberculosisand Lung Disease, 14(4): 379. [IIDMM]

Bekker, L. and Wood, R. 2010. The changing natural history of tuberculosis and HIV coinfection in an urban area of hyperendemicity. Clinical Infectious Diseases, 50(S3): S208-S214. [IIDMM]

Benatar, S.R. and Singer, P. 2010. Responsibilities in international research: a new look revisited. Journal of Medical Ethics, 36(4): 194-197.

Benatar, S.R. and Upsher, R. 2010. Tuberculosis and poverty: what could(and should) be done? International Journal of Tuberculosis and Lung Disease, 14(10): 1215-1221.

Benatar, S.R., Gill, S. and Bakker, I. 2009. Making progress in global health: the need for new paradigms. International Affairs, 85(2): 347-371.

Benatar, S.R., Lister, G. and Thacker, S.C. 2010. Values in global health governance. Global Public Health, 5(2): 143-153.

Bendavid, E., Brandeau, L., Wood, R. and Owens, D.K. 2010. Comparative effectiveness of HIV testing and treatment in highly endemic regions. Archives of InternalMedicine, 170(15): 1347-1354. [IIDMM]

Bere, A., Denny, L.A., Hanekom, W.A., Burgers, W. and Passmore, J.S. 2010. Comparison of polyclonal expansion methods to improve the recovery of cervical cytobrush-derived T cells from the female genital tract of HIV-infected women. Journal ofImmunological Methods, 354(1-2): 68-79. [IIDMM]

Berry, M.P.R., Graham, C.M., McNab, F.W., Xu, Z., Block, S.A.A., Oni, T., Wilkinson, K., Banchereau, R., Skinner, , Wilkinson, R.J., Quinn, C., Blankenship, D., Dhawan, R., Cush, J.J., Mejias, A., Ramilo, O., Kon, O.M., Pascual, V., Banchereau, J., Chaussabel, D. and Garra, A. 2010. An interferon-inducible neutrophil-driven blood transcriptional signature in humna tuberculosis. Nature, 466: 973-977. [IIDMM]

Bhaijee, F., Wainwright, H.C., Meintjes, G., Wilkinson, R.J., Todd, G., de Vries, E. andPepper, D.J. 2010. Warfarin-induced skin necrosis in HIV-infected patients with tuberculosis and venous thrombosis. SAMJ South African Medical Journal, 100(6): 372-377. [IIDMM]

Blumberg, L., de Frey, A., Frean, J. and Mendelson, M. 2010. The 2010 FIFA World Cup: communicable disease risks and advice for visitors to South Africa. Journalof Travel Medicine, 17(3): 150-152.

Booth, H.L., Miller, R.F., Scott, J.F., Badri, M., Huggett, J., Rook, G., Zumla, A., Dheda, K. and Pooran, A. 2010. Different screening strategies (single or dual) for the diagnosis of suspected latent tuberculosis: a cost effectiveness analysis. BMC Pulmonary Medicine, 10(7): 1-14.

Bornman, P.C., Botha, J.F., Ramos, J.M., Smith, M.D., van der Merwe, S., Watermeyer, G. and Ziady, C. 2010. Guideline for the diagnosis and treatment of chronic pancreatitis. SAMJ South African Medical Journal, 100(12): 847-859.

Bose, A., Smith, P.J., Lategan, C.A., Gupta, J.K. and Si, S. 2010. Studies on in vitro antiplasmodial activity of cleome rutidosperma. Acta Poloniae Pharmaceutica, 67(3): 315-318.

Boulle, A.M., Clayden, P., Cohen, K., Cohen, T., Conradie, F., Dong, K., Geffen, N., Grimwood, A., Hurtado, R., Kenyon, C., Lawn, S.D., Maartens, G., Meintjes, G., Mendelson, M., Murray, M., Rangaka, M.X., Sanne, I., Spencer, D., Taljaard, J., Variava, E., Venter, W.D. and Wilson, D. 2010. Prolonged deferral of antiretroviral therapy in the SAPIT trial: did we need a clinical trial to tell us that this would increase mortality? SAMJ South African Medical Journal, 100(9): 566-571. [IIDMM]

Boulle, A.M., Van Cutsem, G., Hilderbrand, K., Cragg, C., Abrahams, M., Mathee, S., Ford, N., Knight, L., Osler, M., Myers, J.E., Goemaere, E., Coetzee, D.J. and Maartens, G. 2010. Seven-year experience of a primary care antiretroviral treatment programme in Khayelitsha, South Africa. AIDS, 24: 563-572. [IIDMM]

Bousquet, J., Shunemann, H., Zuberbier, T., Bachert, C., Baena-Cagnani, C.E., Bousquet, P.J., Brozek, J., Canonica, G.W., Casale, T., Demoly, P., Gerth Van Wijk, R., Ohta, K., Bateman, E.D., Calderon, M., Cruz, A.A., Dolen, W.K., Haughney, J., Lockey, j., Lotvall, J., O'Byrne, P., Spranger, O., Togias, A., Bonini, S., Boulet, L.-P., Camargos, P., Carlsen, K.-H., Chavannes, N.H., Delgado, L., Durham, S.R., Fokkens, W.J., Fonseca, J., Haahtela, T., Kalayci, O., Kowalski, M.L., Larenas-Linnemann, D., Li, J., Mohammad, Y., Mullol, J., Naclerio, R., O'Hehir, R.E., Papadopoulos, N., Passalacqua, G., Rabe, K., Pawankar, R., Ryan, D., Samolinski, B., Simons, F.E.R., Valovirta, E., Yorgancioglu, A., Yusuf, O.M., Agache, I.,Ait-Khaled, N., Annesi-Maesano, I., Motala, C. and Zar, H.J. 2010. Development and implementation of guidelines in allergic rhinitis - an ARIA-GA2LEN paper. Allergy, 65: 1212-1221.

Bousquet, P.J., Kiley, J., Bateman, E.D. and Viegi, G. 2010. Prioritised research agenda for prevention and control of chronic respiratory diseases. European RespiratoryJournal, 36: 995-1001.

Brinkhof, M.W.G., Spycher, B.D., Yiannoutsos, C., Weigel, R., Wood, R., Messou, E., Boulle, A.M., Egger, M. and Sterne, J.A.C. 2010. Adjusting mortality for loss to follow-up: analysis of five ART programmes in Sub-Saharan Africa. PLoS One, 5(11): 10.1371/journal.pone.0014149. [IIDMM]

Bryer, A., Connor, M., Haug, P., Cheyip, B., Staub, H., Tipping, B.N., Duim, W. andPinkney-Atkinson, V. 2010. South African guideline for management of ischaemic stroke and transient ischaemic attack 2010: a guideline from the South African Stroke Society (SASS) and the SASS Writing Committee. SAMJ South African Medical Journal, 100(11): 750-778.

Burrell, E., Mark, D., Grant, R., Wood, R. and Bekker, L. 2010. Sexual risk behaviours and HIV-1 prevalence among urban men who have sex with men in Cape Town, South Africa. Sexual Health, 7: 149-153. [IIDMM]

Byrne, P.M., Reddel, H.K., Eriksson, G., Ostlund, O., Peterson, S., Sears, M.R., Jenkins, C., Humbert, M., Buhl, R., Harrison, T.W., Quirce, S. and Bateman, E.D. 2010. Measuring asthma control: a comparison of three classification systems. European Respiratory Journal, 36: 269-276.

Cashmore, T., Peter, J., Van Zyl Smit, R., Semple, P.L., Maredza, A., Meldau, R., Zumla, A., Nurse, B. and Dheda, K. 2010. Feasibility and diagnostic utility of antigen-specific interferon-γresponses for rapid immunodiagnosis of tuberculosis using induced sputum. PLoS One, 5(4): e10389.

Chatterjee, A., D'souza, D.T.B., Vira, T.S., Bamne, A., Ambe, G.T., Nicol, M., Wilkinson, R.J. and Mistry, N.F. 2010. Strains of Mycobacterium tuberculosis from Western Maharashtra, India, exhibit a high degree of diversity and strain-specific associations with drug resistance, cavitary disease and treatment failure. Journal ofClinical Microbiology, 48(10): 3593-3599. [IIDMM]

Chatterjee, K. 2010. Host genetic factors in susceptibility to HIV-1 infection and progression to AIDS. Journal of Genetics, 89(1): 109-116.

Chellan, P., Shunmoogam-Gouder, N., Hendricks, D.T., Gut, J., Rosenthal, P.J., Lategan, C., Smith, P.J., Chibale, K. and Smith, G.S. 2010.Synthesis, structure and in vitro biological screening of palladium(II) complexes of functionalised salicylaldimine thiosemicarbazones as antimalarial and anticancer agents. European Journal of Inorganic Chemistry, 2010: 3520-3528. [IIDMM]

Chin, A. and Casey, M. 2010. Variant angina complicated by polymorphic ventricular tachycardia (Letter to the Editor). International Journal of Cardiology, 145: e47-e49.

Chukwujekwu, J., Lategan, C.A., Smith, P.J., van Heerden, F.R. and Van Staden, J. 2009. Antiplasmodial and cytotoxic activity of isolated sesquiterpene lactones from the acetone leaf extract of vernonia colorata. South African Journal ofBotany, 75(1): 176-179.

Chun, R.F., Lauridsen, A.L., Suon, L., Zella, L.A., Pike, W.J., Modlin, R.L., Martineau, A.,Wilkinson, R.J., Adams, J. and Hewison, M. 2010. Vitamin D-binding protein directs monocyte reseponses to 25-hydroxy- an 1,25-dhydroxyvitamin D. Journal of Clinical Endocrinology and Metabolism, 95(7): 3368-3376. [IIDMM]

Cohen, K. and Meintjes, G. 2010. Management of individuals requiring ART and TB treatment. Current Opinion in HIV and AIDS, 5(1): 61-69.

Colvin, C., Fairall, L., Lewin, S.A., Georgeu, D., Zwarenstein, M., Bachmann, M.O.,Uebel, K. and Bateman, E.D. 2010. Expanding access to ART in South Africa: the role nurse-initiated treatment. SAMJ South African Medical Journal, 100(4): 210-212.

Connell, T.G., Davies, M., Johannisen, C.F., Wood, K.A., Pienaar, S.M., Wilkinson, K., Wilkinson, R.J., Zar, H.J., Beatty, D.W., Nicol, M.P., Curtis, N. and Eley, B.S. 2010. Reversion and conversion of Mycobacterium tuberculosisIFN-γ ELISpot results during anti-tuberculosis treatment in HIV-infection children. BMCInfectious Diseases, 10:138. [Online]. http://www.biomedcentral.com/1471-2334/10/138. [IIDMM]

Cornell, M., Grimsrud, A.T., Fairall, L., Fox, M.P., Van Cutsem, G., Giddy, J., Wood, R., Prozesky, H., Mohapi, L., Graber, C., Egger, M., Boulle, A.M. and Myer, L. 2010. Temporal changes in programme outcomes among adult patients initiating antiretroviral therapy across South Africa, 2002-2007. AIDS, 24(14): 2263-2270. [IIDMM]

Cunnington, M.S., Koref, M.S., Mayosi, B.M., Burn, J. and Keavney, B. 2010. Chromosome 9p21 SNPs associated with multiple disease phenotypes correlate with ANRIL expression. PloS Genetics, 6(4): e1000899.

Dahya, V. and Spottiswoode, B. 2010. Cardiovascular magnetic resonance imaging – apictorial review. SA Journal of Radiology, December: 92-96.

Dawson, R., Masuka, P., Edwards, D., Bateman, E.D., Bekker, L., Wood, R. and Lawn, S.D. 2010. Chest radiograph reading and recording system: evaluation for tuberculosis screening in patients with advanced HIV. International Journal ofTuberculosis and Lung Disease, 14(1): 52-58. [IIDMM]

Decloedt, E.H. and Stein, D.J. 2010. Current trends in drug treatment of obsessive-compulsive disorder. Neuropsychiatric Disease and Treatment, 6: 233-242.

Decloedt, E.H., Leisegang, R., Blockman, M. and Cohen, K. 2010. Dosage adjustment in medical patients with renal impairment at Groote Schuur Hospital. SAMJ South African Medical Journal, 100(5): 304-306.

Deshpande, G.P., McCarthy, J., Mardikar, H., Lecour, S. and Opie, L.H. 2010. Effects of sphingosine-1-phosphate on acute contractile heart failure (ACHF). Cardiovascular Drugs and Therapy, 24: 459-460.

Dheda, K., Davids, V., Lenders, L., Roberts, T., Meldau, R., Ling, D., Brunet, L., Van Zyl Smit, R., Peter, J., Green, C., Badri, M., Sechi, L.A., Sharma, S.K., Hoelscher, M., Dawson, R., Whitelaw, A.C., Blackburn, J., Pai, M.and Zumla, A. 2010. Clinical utility of a commercial LAM-ELISA assay for TB diagnosis in HIV-infected patients using urine and sputum samples. PLoS One, 5(3): e9848. doi:10.1371/journal.pone.0009848. [IIDMM]

Dheda, K., Schwander, S.K., ZHU, B., Van Zyl Smit, R. and Zhang, Y. 2010. The immunology of tuberculosis: from bench to bedside. Respirology, 15: 433-450.

Dheda, K., Shean, S., Zumla, A., Badri, M., Streicher, E.M., Page-Shipp, L., Willcox, P.A., John, M.-A., Reubenson, G., Govindsamy, D., Wong, M., Padanilam, X., Dziwiecki, A., Van Helden, P., Siwendu, S.N., Jarand, J., Menezes, C.N., Burns, A., Victor, T., Warren, R.M., Grobusch, M.P., Van derWalt, M. and Kvasnovsky, C. 2010. Early treatment outcomes and HIV status of patients with extensively drug-resistant tuberculosis in South Africa: a retrospective cohort study. Lancet, 375: 1798-1807. [IIDMM]

Dheda, K., Warren, R.M., Zumla, A. and Grobusch, M.P. 2010. Extensively drug-resistant tuberculosis: epidemiology and management challenges. InfectiousDisease Clinics of North America, 24: 705-725.

Diacon, A., Dawson, R., Hanekom, M., Narunsky, K., Maritz, S.J., Venter, A., Donald, P.R., van Niekerk, C., Whitney, K., Rouse, D.J., Laurenzi, M.W., Ginsberg, A.M. and Spigelman, M.K. 2010. Early bactericidal activity and pharmacokinetics of PA-824 in smear-positive tuberculosis patients. AntimicrobialAgents and Chemotherapy, 54(8): 3402-3407.

Distiller, G., Little, F. and Barnes, K.I. 2010. Nonlinear mixed effects modeling of gametocyte carriage in patients with uncomplecated malaria. Malaria Journal, 9(60): 1-12. http://www.malariajournal.com/content/9/1/60.

Ekpebegh, C.O., Longo-Mbenza, B., Akinrinmade, A., Blanco-Blanco, E., Badri, M. andLevitt, N.S. 2010. Hyperglycaemic crisis in the Eastern Cape province of South Africa: high mortality and association of hyperosmolar ketoacidosis with a new diagnosis of diabetes. SAMJ South African Medical Journal, 100(12): 822-826.

Elsherbiny, D., Ren, Y., McIlleron, H., Maartens, G. and Simonsson, U. 2010. Population pharmacokinetics of lopinavir in combination with rifampicin-based antitubercular treatment in HIV-infected South African children. European Journal ofClinical Pharmacology, 66: 1017-1023.

Erdmann, J.B., Shepherd, D., Martin, D.P., Varsani, A., Rybicki, E.P. and JESKE, H. 2010. Replicative intermediates of maize streak virus found during leaf development. Journal of General Virology, 91: 1077-1081. [IIDMM]

Essop, M.F., Chan, W., Valle, A., Garcia-Palmer, F.J. and Du Toit, E.F. 2009. Impaired contractile function and mitochondrial repiratory capacity in response to oxgen deprivation in a rat model of pre-diabetes. Acta Physiologica, 197: 289-296.

EVANGELI, M., ENGELBRECHT, S.-K., Swartz, L., Turner, K., FORSBERG, L. andSoka, N.F. 2009. An evaluation of a brief motivational interviewing training course for HIV/AIDS counsellors in Western Cape Province, South Africa. AIDS Care, 21(2): 189-196.

Everett, K., Steyn, K., Mathews, C., Petersen, Z., Odendaal, H., Gwebushe, N. andLombard, C. 2010. The effectiveness of adapted, best practice guidelines for smoking cessation counseling with disadvantaged, pregnant smokers attending public sector antenatal clinics in Cape Town, South Africa. Acta Obstetricia EtGynecologica Scandinavica, 89: 478-489.

Fatti, G.L., Grimwood, A. and Bock, P. 2010. Better antiretroviral therapy outcomes at primary health care facilities: an evaluation of three tiers of ART services in four South African provinces. PLoS One, 5(9): e12888.

Fairall, L., Bachmann, M.O., Zwarenstein, M., Bateman, E.D., Niessen, L., Lombard, C., Majara, B., English, R., Bheekie, A., Van Rensburg, D., Mayers, P.M., Peters, A. andChapman, R. 2010. Cost-effectiveness of educational outreach to primary care nurses in increase tuberculosis case detection and improve respiratory care: economic evaluation alongside a randomised trial. TropicalMedicine & International Health, 15: 277-286.

Fenner, L., Brinkhof, M.W.G., Keiser, O., Weigel, R., Cornell, M., Moultrie, H., Prozesky, H., Technau, K., Eley, B.S., Vaz, P., Pascoe, M., Giddy, J., Van Cutsem, G., Wood, R.,Egger, M. and Davies, M. 2010. Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in southern Africa. JAIDS – Journalof Acquired Immune Deficiency Syndromes, 54(5): 524-532. [IIDMM]

Ferenci, P., Fried, M., Labrecque, D., Bruix, J., Sherman, M., Omata, M., Heathcote, J., Piratsivuth, T., Kew, M.C., Otegbayo, J.A., Zheng, S., Sarin, S., Hamid, S.S., Modawi, S.B., Fleig, W., Fedail, S., Thomson, A., Khan, A.G., Malfertheiner, P., Lau, G., Carillo, F.J., Krabshuis, J.H. and LeMair, A. 2010. Hepatocellular carcinoma (HCC) – A global perspective. Journal ofClinical Gastroenterology, 44(4): 239-245.

Fitzgerald, F.C., Bekker, L., Kaplan, R., Myer, L., Lawn, S.D. and Wood, R. 2010. Mother-to-child transmission of HIV in a community-based antiretroviral clinic in South Africa. SAMJ South African Medical Journal, 100(12): 827-831. [IIDMM]

Fleischer, T., Kevany, S. and Benatar, S.R. 2010. Will escalating spending on HIV treatment displace funding for treatment of other diseases? (Editorial). SAMJ SouthAfrican Medical Journal, 100(1): 32-34.

Fox, M.P., Sanne, I., Conradie, F., Zeinecker, J., Orrell, C., Ive, P., Rassool, M., Dehlinger, M., van der Horst, C., McIntyre, J. and Wood, R. 2010. Initiating patients on antiretroviral therapy at CD4 cell counts above 200 cells/l is associated with improved treatment outcomes in South Africa. AIDS, 24: 2041-2050. [IIDMM]

Gandhi, N.R., Nunn, P., Dheda, K., Schaaf, H., Zignol, M., van Soolingen, D., Jensen, P.and Bayona, J. 2010. Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis. Lancet, 375: 1830-1843.

George, D., Watermeyer, G., Levin, D., Epstein, D., Ross, I.L., Scholz, U., Setshedi, M., Locketz, M.L., Dittrich, C., Shaw, J.M. and Krige, J.E.J. 2010. Composite adrenal phaeochromocytoma-ganglioneuroma causing watery diarrhoea, hypokalaemia and achlorhydria syndrome. European Journal of Gastroenterology &Hepatology, 22(5): 632-634.

Gersh, B., Sliwa, K., Mayosi, B.M. and Yusuf, S. 2010. The epidemic of cardiovascular disease in the developing world: global implications. European HeartJournal, 31: 642-648.

Gideon, H., Wilkinson, K., Rustad, T.G., Oni, T., Guio, H., Kozak, R.A., Sherman, D.R., Meintjes, G., Behr, M., Vordermeier, H., Young, D.B. and Wilkinson, R.J. 2010. Hypoxia induces an immunodominat target of tuberculosis specific T cells absent from common BCG vaccines. PLoS Pathogens, 6(12): e1001237. [IIDMM]

Goedecke, J.H., Utzschneider, K.M., Faulenbach, M.V., Rizzo, M., Berneis, K., Spinas, G.A., Dave, J.A., Levitt, N.S., Lambert, E.V., Olsson, T. andKahn, S.E. 2010. Ethnic differences in serum lipoproteins and their determinants in South African women. Metabolism – Clinicaland Experimental, 59: 1341-1350.

Gous, N., Bhimma, R., Kew, M.C. and Kramvis, A. 2010. Retrospective characterization of the S open reading frame of HBV isolated from children with membranous nephropathy treated with interferon-2b. Antiviral Therapy, 15: 61-69.

Grace, M.H., Lategan, C.A., Mbeunkui, F., Graziose, R., Smith, P.J., Raskin, I. and Lila, M.A. 2010. Antiplasmodial and cytotoxic activities of drimane sesquiterpenes from canella winterana. Natural Product Communications, 5(12): 1869-1872.

Grange, J., Adhikari, M., Ahmed, Y., Mwaba, P., Dheda, K., Hoelscher, M. and Zumla, A. 2010. Tuberculosis in association with HIV/AIDS emerges as a major nonobstetric cause of maternal mortality in Sub-Saharan Africa. International Journal ofGynecology & Obstetrics, 108: 181-183.

Guantai, E.M., Ncokazi, K., Egan, T.J., Gut, J., Rosenthal, P.J., Smith, P.J. and Chibale, K. 2010. Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds. Bioorganic & MedicinalChemistry, 18: 8243-8256. [IIDMM]

Haddow, L.J., Colebunders, R., Meintjes, G., Lawn, S.D., Elliott, J.H., Manabe, Y.C., Bohjanen, P.R., Sungkanuparph, S., Easterbrook, P.J., French, M.A. and Boulware, D.R. 2010. Cryptococcal immune reconstitution inflammatory syndrome in HIV-1-infected individuals: proposed clinical case definitions. Lancet Infectious Diseases, 10: 791-802. [IIDMM]

Hanekom, W.A., Lawn, S.D., Dheda, K. and Whitelaw, A.C. 2010. Tuberculosis research update. Tropical Medicine & InternationalHealth, 15(8): 981-989. [IIDMM]

Hans, R.H., Guantai, E.M., Lategan, C., Smith, P.J., Wan, B., Franzblau, S.G., Gut, J.,Rosenthal, P.J. and Chibale, K. 2010. Synthesis, antimalarial and antitubercular activity of acetylenic chalcones. Bioorganic & Medicinal Chemistry Letters, 20: 942-944. [IIDMM]

Harding, R., Selman, L., Agupio, G. and Mashao, T. 2010. Validation of a core outcome measure for palliative care in Africa: the APCA African Palliative Outcome Scale. Health and Quality of Life Outcomes, 8(10): doi:10.1186/1477-7525-8-10.

Harries, A.D., Zachariah, R., Corbett, E.L., Lawn, S.D., Santos-Filho, E.T., Chimzizi, R.,Harrington, M., Maher, D., Williams, B. and De Cock, K.M. 2010. The HIV-associated tuberculosis epidemic – whenwill we act? Lancet, 375: 1906-1919. [IIDMM]

Harries, A.D., Zachariah, R., Lawn, S.D. and Rosen, S. 2010. Strategies to improve patient retention on antiretroviral therapy in sub-Saharan Africa. Tropical Medicine & International Health, 15(1): 70-75. [IIDMM]

Hausenloy, D.J., Baxter, G., Bell, R., Botker, E., Davidson, S.M., Downey, J., Heusch, G., Kitakaze, M., Lecour, S., Mentzer, R., Mocanu, M.M., Ovize, M., Schultz, R., Shannon, R., Walker, M., Walkinshaw, G. and Yellon, D.M. 2010. Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations. Basic Research in Cardiology, 105: 677-686.

Heckmann, J.M., Pillay, K., Hearn, A.P. and Kenyon, C. 2010. Polymyositis in African HIV-infected subjects. Neuromuscular Disorders, 20: 735-739.

Heckmann, J.M., Uwimpuhwe, H., Ballo, R., Kaur, M., Bajic, V. and Prince, S. 2010. A functional SNP in the regulatory region of the decay-accelerating factor gene associates with extraocular muscle pareses in myasthenia gravis. Genes and Immunity, 11(1): 1-10.

Hendricks, N., Watkins, D.A. and Mayosi, B.M. 2010. Lessons from the first report of the Arrhythmogenic Right Ventricular Cardiomyopathy Registry of South Africa. (Editorial). Cardiovascular Journal of Africa, 21(3): 129-130.

Hodkinson, P. and Wallis, L.A. 2009. Cross-sectional survey of patients presenting to a South African urban emergency centre. Emergency Medicine Journal, 26(9): 635-640.

Hunter, S., Apweiler, R., Attwood, T.K., Bairoch, A., Bateman, A., Binns, P., Bork, P., Das, U., Daugherty, L., Duquenne, L., Finn, R.D., Gough, J., Haft, D., Hulo, N., Kahn, D., Kelly, E., Laugraud, A., Letunic, I., Lonsdale, D., Lopez, R., Madera, M., Maslen, J., McAnulla, C., McDowall, J., Mistry, J., Mitchell, A., Mulder, N.J., Natale, D., Orengo, C., Quinn, A.F., Selengut, J.D., Sigrist, C.J.A., Thimma, M., Thomas, P.D., Valentin, F., Wilson, D., Wu, C.H. and Yeats, C. 2009. InterPro: the integrative protein signature database. Nucleic Acids Research, 36(S1): D211-D215. [IIDMM]

Imazio, M., Brucato, A., Mayosi, B.M., Derosa, F.G., Lestuzzi, C., Macor, A., Trinchero, R., Spodick, D.H. and Adler, Y. 2010. Medical therapy of pericardial disease. Part I: idiopathic and infectious pericarditis. Journal ofCardiovascular Medicine, 11: 712-722.

Imazio, M., Brucato, A., Mayosi, B.M., Derosa, F.G., Lestuzzi, C., Macor, A., Trinchero, R., Spodick, D.H. and Adler, Y. 2010. Medical therapy of pericardial diseases. Part II: noninfectious pericarditis, pericardial effusion and constrictive pericarditis. Journal of Cardiovascular Medicine, 11: 785-794.

Imazio, M., Mayosi, B.M., Brucato, A. and Adler, Y. 2010. Pericardial effusion triage. International Journal of Cardiology, 145(2): 403-404.

Imazio, M., Mayosi, B.M., Brucato, A., Markel, G., Trinchero, R., Spodick, D.H. andAdler, Y. 2010. Triage and management of pericardial effusion. Journal ofCardiovascular Medicine, 11: 928-935.

Ingle, S.M., May, M., Uebel, K., Timmerman, V., Kotze, E., Buchmann, M., Sterne, J.A.C., Egger, M. and Fairall, L. 2010. Differences in access and patient outcomes across antiretroviral treatment clinics in the Free State province: a prospective cohorot study. SAMJ South African Medical Journal, 100(10): 675-681.

Ingle, S.M., May, M., Uebel, K., Timmerman, V., Kotze, E., Bachmann, M.O., Sterne, J.A.C., Egger, M. and Fairall, L. 2010. Outcomes in patients waiting for antiretroviral treatment in the Free State Province, South Africa: prospective linkage study. AIDS, 24(17): 2717-2725.

Janot, L., Sirard, J.-C., Secher, T., Noulin, N., Fick, L., Akira, S., Uematsu, S.,Didierlaurent, A., Hussell, T., Ryffel, B. and Erard, F. 2009. Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin. European Journal of Immunology, 39(6): 1587-1596.

Jarand, J., Shean, K., O'Donnell, M.R., Loveday, M., Kvasnovsky, C., Van der Walt, M., Adams, S., Wilcox, P., O'Grady, J., Zumla, A. and Dheda, K. 2010. Extensively drug-resistant tuberculosis (XDR-TB) among health care workers in South Africa. Tropical Medicine & International Health, 15(10): 1179-1184.

Jarvis, J.N., Harrison, T., Corbett, E.L., Wood, R. and Lawn, S.D. 2010. Is HIV-associated tuberculosis a risk factor for development of cryptococcal disease? AIDS, 24(4): 612-614. [IIDMM]

Jarvis, J.N., Lawn, S.D., Wood, R. and Harrison, T. 2010. Cryptococcal antigen screening for patients initiating antiretroviral therapy: time for action. Clinical InfectiousDiseases, 51(12): 1463-1465. [IIDMM]

Jarvis, J.N., Meintjes, G. and Harrison, T. 2010. Outcomes of cryptococcal meningitis in antiretroviral naive and experienced patients in South Africa. Journal ofInfection, 60(6): 496-498.

Jarvis, J.N., Meintjes, G., Williams, A., Brown, Y., Crede, T. and Harrison, T. 2010. Adult meningitis in a setting of high HIV and TB prevalence: findings from 4961 suspected cases. BMC Infectious Diseases, 10:67. doi:10.1186/1471-2334-10-67.

Jarvis, J.N., Meintjes, G., Williams, Z., Rebe, K. and Harrison, T. 2010. Symptomatic relapse of HIV-associated cryptococcal meningitis in South Africa: the role of inadequate secondary prophylaxis. SAMJ South African Medical Journal, 100(6): 378-382.

Jarvis, J.N., Meintjes, G., Wood, R. and Harrison, T. 2010. Testing but not treating: missed opportunities and lost lives in the South African ART programme. AIDS, 24(8): 1233-1235. [IIDMM]

Jarvis, J.N., Wainwright, H.C., Harrison, T., Rebe, K. and Meintjes, G. 2010. Pulmonary crptococcosis misdiagnosed as smear-negative pulmonary tuberculosis with fatal consequences. International Journal of Infectious Diseases, 14S: e310-e312.

Jaspan, H.B., Soka, N.F., Mathews, C., Flisher, A.J., Mark, D., Middelkoop, K., Wood, R. and Bekker, L. 2010. A qualitative assessment of perspectives on the inclusion of adolescents in HIV vaccine trials in South Africa. International Journal ofSTD& AIDS, 21(3): 172-176. [IIDMM]

Joffe, Y., van der Merwe, L., Carstens, M., Collins, M., Jennings, C., Levitt, N.S.,Lambert, E.V. and Goedecke, J.H. 2010. Tumor necrosis factor-alpha gene -308 G/A polymorphism modulates the relationship between dietary fat intake, serum lipids, and obesity risk in black South African women. Journal of Nutrition, 140: 901-907.

Joska, J., Combrinck, M.I., Valcour, V.G., Hoare, J., Leisegang, F., Mahne, A.C., Myer, L. and Stein, D.J. 2010. Association between apolipoprotein E4 genotype and human immunodefiency virus-associated dementia in younger adults starting antiretroviral therapy in South Africa. Journal of Neurovirology, 16: 377-383.

Joubert, M.K., Kinsley, N., Capovilla, A., Sewell, B.T., Jaffer, M.A. and Khati, M. 2010. Amodeled structure of an aptamer-gp120 complex provides insight into the mechanism of HIV-1 neutralization. Biochemistry, 49: 5880-5890. [IIDMM]

Kagina, B., Abel, B., Scriba, T.J., Hughes, E.J., Keyser, A.T., Soares, A.P., Gamieldien, H., Sidibana, M., Hatherill, M., Gelderbloem, S., Mahomed, H., Hawkridge, A., Hussey,G.D., Kaplan, G. and Hanekom, W.A. 2010. Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after Bacillus Calmette-Guerin vaccination of newborns. AmericanJournal of Respiratory and Critical Care Medicine, 182: 1073-1079. [IIDMM]

Kalula, S.Z., Ferreira, M., Thomas, K., De Villiers, L., Joska, J. and Geffen, L. 2010. Profile and management of patients at a memory clinic. SAMJ SouthAfrican Medical Journal, 100(7): 449-451. [IAA]

Kalula, S.Z., Swingler, G.H., Sayer, A.A., Badri, M. and Ferreira, M. 2010. Does chair type influence outcome in the timed "up and go" test in older persons? Journal of Nutrition Health & Aging, 14(4): 319-323. [IAA]

Kaufmann, S.H.E., Hussey, G.D. and Lambert, P.-H. 2010. New vaccines for tuberculosis. Lancet, 375: 2110-2119. [IIDMM]

Kelly, R., Lamont, K., Somers, S., Hacking, D., Lacerda, L., Thomas, P., Opie, L.H. andLecour, S. 2010. Ethanolamine is a novel STAT-3 dependent cardioprotective agent. Basic Research in Cardiology, 105: 763-770.

Kenyon, C. and Badri, M. 2009. The role of concurrent sexual relationships in the spread of sexually transmitted infections in young South Africans. Southern AfricanJournal of HIV Medicine, 10(1): 29-36.

Kenyon, C., Boulle, A.M., Badri, M. and Asselman, V. 2010. "I don't use a condom (with my regular partner) because I know that I'm faithful, but with everyone else I do": the cultural and socioeconomic determinants of sexual partner concurrency in young South Africans. SAHARA: Journal of Social Aspects of HIV/AIDS, 7(3): 35-43.

Kenyon, C., Pillay, K. and Heckmann, J.M. 2010. Beware of 'normal' creatine kinase levels in HIV-associated polmyositis. SAMJ South African Medical Journal, 100(3): 156-157.

Kenyon, C., Zondo, S. and Badri, M. 2010. Determinants of self-perceived HIV risk in young South Africans engaged in concurrent sexual relationships. African Journal ofReproductive Health, 14(3): 171-182.

Kew, M.C. 2010. Epidemiology of chronic hepatitis B virus infection, hepatocellular carcinoma, and hepatitis B virus-induced hepatocellular carcinoma. Pathologie Biologie, 58: 273-277.

Khanye, S.D., Smith, G.S., Lategan, C., Smith, P.J., Gut, J., Rosenthal, P.J. andChibale, K. 2010. Synthesis and in vitro evaluation of gold(I) thiosemicarbazone complexes for antimalarial activity. Journal of Inorganic Biochemistry, 104: 1079-1083. [IIDMM]

Khati, M. 2010. The future of aptamers in medicine. Journal of Clinical Pathology, 63: 480-487.

Kiechl, S., Laxton, R.C., Xiao, Q., Hernesniemi, J.A., Raitakari, O.T., Kahonen, M., Mayosi, B.M., Jula, A., Moilanen, L., Willeit, J., Watkins, H., Samani, N.J., Lehtimaki, T.J., Keavney, B., Xu, Q. and Ye, Y. 2010. Coronary artery disease-related genetic variant on chromosome 10q11 is associated with carotid intima-media thickness and atherosclerosis. Arteriosclerosis Thrombosis and VascularBiology, 30: 2678-2683.

Kim, M.-J., Wainwright, H.C., Locketz, M.L., Bekker, L., Walther, G., Dittrich, C., Visser, A., Wang, W., Hsu, F.-F., Weihart, U., Tsenova, L., Kaplan, G. and Russell, D.G. 2010. Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism. EMBO Molecular Medicine, 2(7): 258-274. [IIDMM]

Kimberlin, D.W., Jacobs, R.F., Weller, S., Van der Walt, J.-S., Heitman, C.K., Man, C.Y.and Bradley, J.S. 2010. Pharmacokinetics and safety of extemporaneously compounded valacyclovir oral suspension in pediatric patients from 1 month through 11 years of age. Clinical Infectious Diseases, 50: 221-228.

Kozuki, A., Shite, J., Shinke, T., Miyoshi, N., Sawada, T., Hellig, F., Abelson, M., Brown, B., Khan, S., Mpe, M., Ntsekhe, M., Conway, M.A. and Hirata, K.-I. 2010. STELLIUM1: First-in-man follow-up evaluation of bioabsorbable polymer-coasted paclitaxel-eluting stent. Circulation Journal, 74: 2089-2096.

Kranzer, K., Bekker, L., Van Schaik, N., Thebus, L., Dawson, M., Caldwell, J., Hausler, H., Grant, R. and Wood, R. 2010. Community health care workers in South Africa are at increased risk for tuberculosis. SAMJ South AfricanMedical Journal, 100(4): 224-226. [IIDMM]

Kranzer, K., Houben, R.M.G.J., Glynn, J.R., Bekker, L., Wood, R. and Lawn, S.D. 2010. Yield of HIV-associated tuberculosis during intensified case finding in resource-limited settings: a systematic review and meta-analysis. Lancet InfectiousDiseases, 10: 93-102. [IIDMM]

Kranzer, K., Lewis, J.J., Ford, N., Zeinecker, J., Orrell, C., Lawn, S.D., Bekker, L. andWood, R. 2010. Treatment interruption in a primary care antiretroviral therapy program in South Africa: cohort analysis of trends and risk factors. JAIDS – Journalof Acquired Immune Deficiency Syndromes, 55(3): e17-e23. [IIDMM]

Kranzer, K., Zeinecker, J., Ginsberg, P., Orrell, C., Kalawe, N.N., Lawn, S.D., Bekker, L.and Wood, R. 2010. Linkage to HIV care and antiretroviral therapy in Cape Town, South Africa. PLoS One, 5(11): e13801. [IIDMM]

Lacerda, L., McCarthy, J., Mungly, S.F.K., Lynn, E.G., Sack, M.N., Opie, L.H. andLecour, S. 2010. TNF(alpha) protects cardica mitochondria independently of its cell surface receptors. Basic Research in Cardiology, 105: 751-762.

Latib, A., Colombo, A. and Sangiorgi, G.M. 2009. Bifurcation stenting:current strategies and new devices. Heart, 95(6): 495-504.

Latib, A., Ferri, L., Lelasi, A., Cosgrave, J., Godino, C., Bonizzoni, E., Romagnoli, E., Chieffo, A., Valgimigli, M., Penzo, C., Carlino, M., Michev, I., Sangiorgi, G.M.,Montorfano, M., Airoldi, F. and Colombo, A. 2010. Comparison of the long-term safety and efficacy of drug-eluting and bare-metal stent implantation in saphenous vein grafts. Circulation-Cardiovascular Interventions, 3: 249-256.

Latib, A., Ferri, L., Lelasi, A., Godino, C., Chieffo, A., Magni, V., Bassanelli, G., Sharp, A.S.P., Gerber, R., Michev, I., Carlino, M., Airoldi, F., Sangiorgi, G.M., Montorfano, M.and Colombo, A. 2009. Clinical outcomes after unrestricted implantation of everolimus-eluting stents. JACC-Cardiovascular Interventions, 2(12): 1219-1226.

Lawn, S.D. and Wilkinson, R.J. 2010. Primate model to study reactivation of TB associated with retroviral infection. Future Virology, 5(4): 391-395. [IIDMM]

Lawn, S.D. and Wood, R. 2010. Antiretroviral therapy for control of the HIV-associated MDR and XDR tuberculosis epidemic in South Africa. American Journal ofRespiratory and Critical Care Medicine, 182(12): 1567. [IIDMM]

Lawn, S.D. and Wood, R. 2010. Immune reconstitution inflammatory syndrome. Lancet Infectious Diseases, 10(12): 833-834. [IIDMM]

Lawn, S.D., Edwards, D. and Wood, R. 2010. Reducing the burden of tuberculosis presenting during the initial months of antiretroviral therapy in resource-limited settings (Editorial). Clinical Infectious Diseases, 50: 124-125. [IIDMM]

Lawn, S.D., Harries, A.D. and Wood, R. 2010. Strategies to reduce early morbidity and mortality in adults receiving antiretroviral therapy in recource-limited settings. Current Opinion in HIV and AIDS, 5: 18-26. [IIDMM]

Lawn, S.D., Kranzer, K., Edwards, D., McNally, M., Bekker, L. and Wood, R. 2010. Tuberculosis during the first year of antiretroviral therapy in a South Afria cohort using an intensive pretreatment screening strategy. AIDS, 24: 1323-1328. [IIDMM]

Lawn, S.D., Wood, R., De Cock, K.M., Kranzer, K., Lewis, J.J. and Churchyard, G.J. 2010. Antiretrovirals and isoniazid preventive therapy in the prevention of HIV-associated tuberculosis in settings with limited health-care resources. Lancet Infectious Diseases, 10: 489-498. [IIDMM]

Leisegang, R., Maartens, G., Hislop, M., Regensberg, L. and Cleary, S. 2010. Improving the evidence base of Markov models used to estimate the costs of scaling up antiretroviral programmes in resource-limited settings. BMC Health ServicesResearch, 10(1). doi:10.1186/1472-6963-10-S1-S3.

Lelasi, A., Latib, A., Godino, C., Sharp, A.S.P., Lamee, R.A., Montorfano, M., Airoldi, F.,Carlino, M., Chieffo, A., Sangiorgi, G.M. and Colombo, A. 2010. Clinical outcomes following protected carotid artery stenting in symptomatic and asymptomatic patients. Journal of Endovascular Therapy, 17: 298-307.

Lenders, L., Meldau, R., Van Zyl Smit, R., Woodburne, V.E., Maredza, A., Cashmore, T.,Semple, P.L., Badri, M., Zumla, A. and Dheda, K. 2010. Comparison of same day versus delayed enumeration of TB-specific T cell responses. Journal of Infection, 60: 344-350.

Li, R., Jaspan, H.B., O'Brien, V., Cotton, R.G.H., Rabie, H. and Nattrass, N.J. 2010. Positive futures:  a qualitative study on the needs of adolescents on antiretroviral therapy in South Africa. AIDS Care – Psychologicaland Socio-Medical Aspects ofAIDS/HIV, 22(6): 751-758. [IIDMM]

Lombard, M.C., N'Da, D.D., Breytenbach, J.C., Smith, P.J. and Lategan, C.A. 2010. Artemisinin-quinoline hybrid-dimers: synthesis and in vitro antiplasmodial activity. Bioorganic & Medicinal Chemistry Letters, 20: 6975-6977.

Lourens, C., Watkins, W., Barnes, K.I., Sibley, C.H., Guerin, P.J., White, N. andLindegardh, N. 2010. Implementation of a reference standard and proficiency testing programme by the World Wide Antimalarial Resistance Network (WWARN). Malaria Journal, 9:375. doi:10.1186/1475-2875-9-375.

Louw, P., Maritz, D. and Wallis, L.A. 2010. Emergency centres lack defibrillator knowledge. SAMJ South African Medical Journal, 100(7): 435-436.

Loyse, A., Wainwright, H.C., Jarvis, J.N., Bicanic, T., Rebe, K., Meintjes, G. andHarrison, T. 2010. Histopathology of the arachnoid granultions and brain in HIV-associated cryptococcal meningitis: correlation with cerebrospinal fluid pressure. AIDS, 24: 405-410.

Ma, Z., Lienhardt, C., McIlleron, H., Nunn, A.J. and Wang, X. 2010. Global tuberculosis drug development pipeline: the need and the reality. Lancet, 375(9731): 2100-2109.

Mall, A.S., Tyler, M., Ho, S.B., Krige, J.E.J., Kahn, D., Spearman, W., Myer, L. andGovender, D. 2010. The expression of MUC mucin in cholangiocarcinoma. Pathology Research and Practice, 206(12): 805-809.

Mao, M., Matimba, A., Scordo, M., Gunes, A., Zengil, H., Yasui-Furukori, N.,Masimirembwa, C.M. and Dahl, M.L. 2009. Flavin-containing monooxygenase 3 polymorphisms in 13 ethnic populations from Europe, East Asia and sub-Saharan Africa:frequency and linkage analysis. Pharmacogenomics, 10(9): 1447-1455.

Marais, B., Hoelscher, M., Mwaba, P., Dheda, K. and Zumla, A. 2010. World TB Day 2010: eradicating tuberculosis in Sub-Saharan Africa needs effective and committed north-south partnerships (Editorial). SAMJ South African Medical Journal, 100(3): 153-154.

Marais, S., Pepper, D.J., Marais, B. and Torok, M.E. 2010. HIV-associated tuberculous meningitis – diagnosticand therapeutic challenges. Tuberculosis, 90: 367-374.

Marais, S., Scholtz, P., Pepper, D.J., Meintjes, G., Wilkinson, R.J. and Candy, S. 2010. Neuroradiological features of the tuberculosis-associated immune reconstitution inflammatory syndrome. International Journal of Tuberculosis and LungDisease, 14(2): 188-196. [IIDMM]

Marais, S., Thwaites, G., Schoeman, J., Torok, M.E., Misra, U.K., Prasad, K., Donald, P.R., Wilkinson, R.J. and Marais, B. 2010. Tuberculous meningitis: a uniform case definition for use in clinical research. Lancet Infectious Diseases, 10: 803-812. [IIDMM]

Maritz, D., Wallis, L.A. and Hardcastle, T. 2009. Complications of tube thoracostomy for chest trauma. SAMJ South African Medical Journal, 99(2): 114-117.

Maritz, J., Benatar, M., Dave, J.A., Harrison, T.B., Badri, M., Levitt, N.S. and Heckmann, J.M. 2010. HIV Neuropathy in South Africans: frequency, characteristics, and risk factors. Muscle & Nerve, 41: 599-606.

Martineau, A., Leandro, A.C.C.S., Anderson, S., Newton, S., Wilkinson, K., Nicol, M.P.,Pienaar, S., Skolimowska, K.e.i.r.a., Rocha, M.A., Rolla, V.C., Levin, M., Davidson, R., Bremner, S.A., Griffiths, C., Eley, B.S., Bonecini-Almeida, M.G. and Wilkinson, R.J. 2010. Association between Gc genotype and susceptibility to TB is dependent on vitamin D status. EuropeanRespiratory Journal, 35: 1106-1112. [IIDMM]

Mash, B., Rhode, H., Pather, M., Ainslie, G.M., Irusen, E., Bheekie, A. and Mayers, P.M. 2010. Evaluation of the Asthma Guideline Implementation Project in the Western Cape, South Africa. Current Allergy & Clinical Immunology, 23(4): 154-161.

Masters, K., Ng'ambi, D. and Todd, G. 2010. "I found it on the Internet". Preparing for the e-patient in Oman. Sultan Quaboos University Medical Journal, 10(2): 169-179.

May, M., Boulle, A.M., Phiri, , Messou, E., Myer, L., Wood, R., Keiser, O., Sterne, J.A.C.,Dabis, F. and Egger, M. 2010. Prognosis of patients with HIV-1 infection starting antiretroviral therapy in sub-Saharan Africa: a collaborative analysis of scale-up programmes. Lancet, 376: 449-457. [IIDMM]

Mayosi, B.M. 2010. The four pillars of rheumatic heart disease control (Editorial). SAMJ South African Medical Journal, 100(8): 506.

McIlleron, H. and Gous, H. 2009. Pharmacokinetics of antiretroviral drugs in infancy. Southern African Journal of HIV Medicine, 36: 54-61.

Medeiros-Domingo, A., Tan, B.-H., Crotti, L., Tester, D.J., Eckhardt, L., Cuoretti, A., Kroboth, S.L., Song, C., Zhou, Q., Kopp, D., Schwartz, P.J., Makielski, J.C. andAckerman, M.J. 2010. Gain-of-function mutation S422L in the KCNJ8-encoded cardiac K(ATP) channel Kir6.1 as a pathogenic substrate for J-wave syndromes. Heart Rhythm, 7: 1466-1471.

Meents, E.F. and Boyles, T.H. 2010. Schistosoma haematobium prevalence in school children in the rural Eastern Cape Province, South Africa. Southern AfricanJournal of Epidemiology and Infection, 25(4): 28-29.

Meintjes, G. and Wilkinson, R.J. 2010. Optimum timing of antiretroviral therapy for HIV-infected patients with concurrent serious opportunistic infections (Editorial). ClinicalInfectious Diseases, 50(11): 1539-1541. [IIDMM]

Meintjes, G. and Wilkinson, R.J. 2010. Undiagnosed active tuberculosis in HIV-infected patients commencing antiretroviral therapy (Editorial). Clinical InfectiousDiseases, 51(7): 830-832. [IIDMM]

Meintjes, G., Wilkinson, R.J., Morroni, C., Pepper, D.J., Rebe, K., Rangaka, M.X., Oni, T. and Maartens, G. 2010. Randomized placebo-controlled trial of prednisone for paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome. AIDS, 24: 2381-2390. [IIDMM]

Mendelson, M. 2010. The scramble for influenza vaccine in 2010 (Editorial). SAMJ South African Medical Journal, 100(7): 428-429.

Mendelson, M. 2010. World Cup Fever. South African Journal of Epidemiology andInfection, 25(1): 3-4.

Mendelson, M., Davis, X.M., Jensenius, M., Keystone, J.S., von Sonnenburg, F., Hale, D.C., Burchard, G.-D., Field, V., Vincent, P. and Freedman, D.O. 2010. Short report: health risks in travelors to South Africa: the GeoSentinel experience and implications for the 2010 FIFA World Cup. American Journal of Tropical Medicine and Hygiene, 82(6): 991-995.

Meurer, M., Einchenfield, L., Ho, V., Potter, P.C., Werfel, T. and Hultsch, T. 2010. Addition of pimecrolimus cream 1% to a topical corticosteroid treatment regimen in paediatric patients with severe atopic dermatitis: a randomized, double-blind trial. Journal of Dermatological Treatment, 21: 157-166.

Micklesfield, L.K., Evans, J., Norris, S.A., Lambert, E.V., Jennings, C., Joffe, Y., Levitt, N.S. and Goedecke, J.H. 2010. Dual-energy X-ray absorptiometry and anthropometric estimates of visceral fat in black and white South African women. Obesity, 18(3): 619-624.

Middelkoop, K., Bekker, L., Myer, L., Whitelaw, A.C., Grant, A., Kaplan, G., McIntyre, J.and Wood, R. 2010. Antiretroviral program associated with reduction in untreated prevalent tuberculosis in a South Africa township. American Journal of Respiratory and Critical Care Medicine, 182: 1080-1085. [IIDMM]

Migliori, G.B., Dheda, K., Centis, R., Mwaba, P., Bates, M., O'Grady, J., Hoelscher, M.and Zumla, A. 2010. Review of multidrug-resistant and extensively drug-resistant TB: global perpectives with a focus on sub-Saharan Africa. Tropical Medicine & International Health, 15(9): 1052-1066.

Mkhize, N., Gumbi, P., Liebenberg, L., Ren, Y., Smith, P.J., Denny, L.A. and Passmore, J.S. 2010. Persistence of genital tract T cell responses in HIV-infected women on highly active antiretrovirual therapy. Journal of Virology, 84(20): 10765-10772. [IIDMM]

Moyo, S., Verver, S., Mahomed, H., Hawkridge, A., Kibel, M.A., Hatherill, M., Tameris, M.D., Geldenhuys, H.D., Hanekom, W.A. and Hussey, G.D. 2010. Age-related tuberculosis incidence and severity in children under 5 years of age in Cape Town, South Africa. International Journal of Tuberculosis and Lung Disease, 14(2): 149-154. [IIDMM]

Mulder, N.J., Rabiu, H., Jamieson, G. and Vuppu, V. 2009. Comparative analysis of microbial genomes to study unique and expanded gene families in Mycobacterium tuberculosis. Infection Genetics and Evolution, 9(3): 314-321. [IIDMM]

Muller, E., Kahn, D. and Mendelson, M. 2010. Renal transplantation between HIV-positive donors and recipients. New England Journal of Medicine, 362(24): 2336-2337.

Nachega, J.B., Chaisson, R.E., Goliath, R., Efron, A., Chaudhary, M.A., Ram, M., Morroni, C., Schoeman, H., Knowlton, A. and Maartens, G. 2010. Randomized controlled trial of trained patient-nominated treatment supporters providing partial directly observed antiretroviral therapy. AIDS, 24: 1273-1280.

Nachega, J., Leisegang, R., Bishai, D., Nguyen, H., Hislop, M., Cleary, S., Regensberg, L. and Maartens, G. 2010. Association of antiretroviral therapy adherence and health care costs. Annals of Internal Medicine, 152: 18-25.

Nakhjavani, N., Brunette, K.E.J., Potter, P.C. and Motala, C. 2010. Beware the rare cause of an acute abdomen. Current Allergy & Clinical Immunology, 23(1): 34-35.

N'Da, D.D., Breytenbach, J.C., Smith, P.J. and Lategan, C.A. 2010. Synthesis, cytotoxicity and antimalarial activity of ferrocenyl amides of 4-aminoquinolines. Arzneimittel-Forschung-Drug Research, 60(10): 627-635.

Nglazi, M., Kaplan, R., Wood, R., Bekker, L. and Lawn, S.D. 2010. Identification of losses to follow-up in a community-based antiretroviral therapy clinic in South Afica using a computerized pharmacy tracking system. BMC Infectious Diseases, 10:329. doi:10.1186/1471-2334-10-329. [IIDMM]

Novitzky, N., Thomson, J., Thomas, V., Du Toit, C.E., Mohamed, Z. and McDonald, A.B. 2010. Combined submyeloablative and myeloablative dose intense melphalan results in satisfactory responses with acceptable toxicity in patients with multiple myeloma. Biology of Blood and Marrow Transplantation, 16(10): 1402-1410.

Ntusi, N. and Heckmann, J.M. 2010. Myopathy with a normal creatine kinase level in juvenile myopathic dermatomyositis. SAMJ South African Medical Journal, 100(1): 24-25.

Ntusi, N., Aubin, L.A., Oliver, S.P., Whitelaw, A.C. and Mendelson, M. 2010. Guidelines for the optimal use of blood cultures. SAMJ South African Medical Journal, 100(12): 839-843.

Ntutela, S., Smith, P., Matika, L., Mukinda, J., Arendse, H.J., Allie, N., Estes, D.M., Mabusela, W., Folb, P.I., Steyn, L.M., Johnson, Q., Folk, W.R., Syce, J. and Jacobs, M. 2009. Efficacy of artemisia afra phytotherapy in experiental tuberculosis. Tuberculosis, 89(1): S33-S40. [IIDMM]

Nussbaum, J.C., Jackson, A., Namarika, D. and Jarvis, J.N. 2010. Combination flucytosine andhigh-dose fluconazole compared with fluconazole monotheraphy for the treatment of cryptococcal meningitis: arandomized trial in Malawi. Clinical Infectious Diseases, 50: 338-344.

Nyunt, M.M., Adam, I., Kayentao, K., van Dijik, J., Mauff, K., Little, F., Cassam, Y., Guirou, E., Traore, B., Doumbo, O., Sullivan, D., Smith, P.J. and Barnes, K.I. 2010. Pharmacokinetics of sulfadoxine and pyrimethamine in intermittent preventive treatment of malaria in pregnancy. Clinical Pharmacology &Therapeutics, 87(2): 226-234.

Odero, A., Bozzani, A., De Ferrari, G.M. and Schwartz, P.J. 2010. Left cardiac sympothetic denervation for the prevention of life-threatening arrhythmias: The surgical supraclavicular approach to cervicothoracic sympathetomy. Heart Rhythm, 7: 1161-1165.

O'Donnell, M.R., Jarand, J., Loveday, M., Padayatchi, N., Zelnick, J., Werner, L., Naidoo, K., Master, I., Osbum, G., Kvasnovsky, C., Shean, S., Pai, M., Van der Walt, M.,Horsburgh, C.R. and Dheda, K. 2010. High incidence of hospital admissions with multidrug-resistant and extensively drug-resistant tuberculosis among South African health care workers. Annals of Internal Medicine, 153: 516-522.

O'Donnell, M., Xavier, D., Diener, C. and De Villiers, L. 2010. Rationale and design of INTERSTROKE: aglobal case-control study of risk factors for stoke. Neuroepidemiology, 35: 36-44.

Okpechi, I.G., Rayner, B.L. and Swanepoel, C.R. 2010. Nephrotic syndrome in adult black South Africans: HIV-associated nephropathy as the main culprit. Journal ofthe National Medical Association, 102(12): 1193-1197.

Okpechi, I.G., Motala, A., Panieri, E. and Rayner, B.L. 2010. Adrenal-oncocytic tumor: an unusual cause of secondary hypertension in a young South African male. Nephrology Reviews, 2(12): 53-55.

Okpechi, I., Rayner, B.L., Van der Merwe, L., Mayosi, B.M., Adeyemo, A., Tiffin, N. and Ramesar, R.S. 2010. Genetic variation at selected SNPs in the leptin gene and association of alleles with markers of kidney disease in a Xhosa population of South Africa. PLoS One, 5(2): e9086. [IIDMM]

Oni, T., Patel, J., Gideon, H., Seldon, R., Wood, K.A., Hlombe, Y., Wilkinson, K.,Rangaka, M.X., Mendelson, M. and Wilkinson, R.J. 2010. Enhanced diagnosis of HIV-1-associated tuberculosis by relating T-SPOT.TB and CD4 counts. European Respiratory Journal, 36(3): 594-600. [IIDMM]

Opie, L.H., Lecour, S., Mardikar, H. and Deshpande, G.P. 2010. Cardiac survival strategies: an evolutionary hypothesis with rationale for metabolic therapy of acute heart failure. Transactions of the Royal Society of South Africa, 65(3): 185-189.

Pandie, M., Sonderup, M., Meissner, P.N. and Mendelson, M. 2010. Acute porphyria precipitated by nevirapine. AIDS, 24(16): 2597-2599. [IIDMM]

Patel, V.B., Singh, R., Connolly, C., Coovadia, Y., Peer, A.K.C., Parag, P., Kasprowicz, V., Zumla, A., Ndung'u, T. and Dheda, K. 2010. Cerebrospinal T-cell responses aid in the diagnosis of tuberculous meningitis in a human immunodeficiency virus- and tuberclosis-endemic population. American Journal ofRespiratory and Critical Care Medicine, 182: 569-577.

Patel, V.B., Singh, R., Connolly, C., Kasprowicz, V., Zumla, A., Ndungu, T. and Dheda, K. 2010. Comparison of a clinical prediction rule and a LAM antigen-detection assay for the rapid diagnosis of TBM in a high HIV prevalence setting. PLoS One, 5(12): e15664.

Pedersen, S., Potter, P.C., Dachev, S., Bosheva, M., Kaczmarek, J., Springer, E.,Dunkel, J. and Engelstatter, R. 2010. Efficacy and safety of three ciclesonide doses vs placebo in children with asthma: the rainbow study. Respiratory Medicine, 104: 1618-1628.

Pepper, D.J., Marais, S., Wilkinson, R.J., Bhaijee, F., Maartens, G., McIlleron, H., Azevedo, V., Cox, H.S., McDermid, C., Sokhela, S., Patel, J. and Meintjes, G. 2010. Clinical deterioration during antituberculosis treatment in Africa: incidence, causes and risks factors. BMC Infectious Diseases, 10:83.doi: 10.1186/1471-2334-10-83. [IIDMM]

Peter, J., Green, C., Hoelscher, M., Mwaba, P., Zumla, A. and Dheda, K. 2010. Urine for the diagnosis of tuberculosis: current approaches, clinical applicability, and new developments. Current Opinion in Pulmonary Medicine, 16: 262-270.

Pillay, S., Shephard, E.G., Meyers, A.E., Williamson, A.-L. and Rybicki, E.P. 2010. HIV-1 sub-type C chimaeric VLPs boost cellular immune responses in mice. Journal of Immune Based Therapies and Vaccines, 8(7): 1-6. [IIDMM]

Potter, P.C. 2010. A therapeutic approach to atopic eczema. South African FamilyPractice, 52(4): 277-282.

Potter, P.C. 2010. Indoor and outdoor allergens in Bloemfontein (Editorial). SAMJ South African Medical Journal, 100(3): 155.

Potter, P.C., Warner, J., Pawankar, R., Kaliner, M.A., Del, G.S. and Rosenwasser, L. 2010. Recommendations for competency in allergy training for undergraduates qualifying as medical practisioners: aposition paper of the World Allergy Organization. Journal of Investigational Allergology and Clinical Immunology, 20(3): 179-184.

RAAL, F., Santos, R.D., Blom, D., Marais, A.D., Charng, M.-J., Cromwell, W.C., Lachmann, R.H., Gaudet, D., Tan, J.L., Chasan-Taber, S., Tribble, D.L., Flaim, J.D. andCrooke, S.T. 2010. Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familialhypercholesterolaemia: a randomised, double-blind, placebo-controlled trial. Lancet, 375: 998-1006.

Rajabally, M., Watermeyer, G. and Levin, D. 2010. A case of Crohn's disease complicated by adult onset Still's Disease. Journal of Crohns & Colitis, 4: 475-478.

Raman, J., Little, F., Roper, C., Kleinschmidt, I., Cassam, Y., Maharaj, R. and Barnes, K.I. 2010. Five years of large-scale dhfr and dhps mutation surveillance following the phased implementation of artesunate plus sulfadoxine-pyrimethamine in Maputo Province, Southern Mozambique. American Journal of Tropical Medicine andHygiene, 82(5): 788-794.

Rayner, B.L. 2010. Hypertension: detection and management in South Africa. Nephron Clinical Practice, 116: c269-c273.

Ross, I.L., Boulle, A.M., Soule, S., Levitt, N.S., Pirie, F., Karlsson, A., Mienie, J., Yang, P., Wang, H., She, J.-X., Winter, W. and Schatz, D. 2010. Autoimmunity predominates in a large South African cohort with addison's disease of mainly European descent despite long-standing disease and is associated with HLA DQB*0201. Clinical Endocrinology, 73: 291-298.

Ross, J., Ehrlich, R.I., Hnizdo, E., White, N.W. and Churchyard, G.J. 2010. Excess lung function decline in gold miners following pulmonary tuberculosis. Thorax, 65: 1010-1015.

Rubbert-Roth, A., Tak, P.P., Zerbini, C., Tremblay, J.-L., Carreno, L., Armstrong, G.,Collinson, N., Shaw, T.M. and Kalla, A.A. 2010. Efficacy and safety of various repeat treatment dosing regimens of rituximab in patients with active rheumatoid arthritis: results of a Phase III randomized study (MIRROR). Rheumatology, 49: 1683-1693.

Rudy, B.J., Kapogiannis, B.G., LALLY, a.a., GRAY, G.E., Bekker, L., KROGSTAD, P. AND MCGOWAN, I. 2010. Youth-specific considerations in the development of preexposure prophylaxis, microbicide, and vaccine research trials. JAIDS – Journalof Acquired Immune Deficiency Syndromes, 54: S31-S42. [IIDMM]

Samuel, C., Maistry, S., Meyer, E. and Whitelaw, A.C. 2010. Pneumocystis jirovecii infection of the external auditory canal. Southern African Journal of HIVMedicine, 38: 39-40.

Sanne, I., Orrell, C., Fox, M.P., Conradie, F., Ive, P., Zeinecker, J., Cornell, M., Heiberg, C., Ingram, C., Panchia, R., Rassool, M., Gonin, R., Stevens, W.S., Truter, H., Dehlinger, M., van der Horst, C., McIntyre, J. and Wood, R. 2010. Nurse versus doctor management of HIV-infected patients receiving antiretroviral therapy (CIPRA-SA):a randomised non-inferiority trial. Lancet, 376: 33-40. [IIDMM]

Schafer, G., Guler, R., Murray, G., Brombacher, F. and Brown, G.D. 2009. The role of scavenger receptor B1 in infection with Mycobacterium tuberculosis in a murine model. PLoS One, 4(12): e8448. [IIDMM][IIDRU]

Schull, M.J., Banda, H., Kathyola, D., Fairall, L., Martiniuk, A., Burciul, B., Zwarenstein, M., Sodhi, S., Thompson, S., Joshua, M., Mondiwa, M. and Bateman, E.D. 2010. Strengthening health human resources and improving clinical outcomes through an integrated guideline and educational outreach in resource-poor settings: a cluster-randomized trial. Trials, 11(118): doi:10.1186/1745-6215-11-118.

Schutz, C., Boulle, A.M., Rebe, K. and Meintjes, G. 2010. Reduced referral and case fatality rates for severe symptomatic hyperlactataemia in a South African public sector antiretroviral programme: a retrospective observational study. AIDS Researchand Theraphy, 7(13): 1-6.

Schutz, C., Meintjes, G., Almajid, F., Wilkinson, R.J. and Pozniak, A. 2010. Clinical management of tuberculosis and HIV-1 co-infection. European RespiratoryJournal, 36(6): 1460-1481. [IIDMM]

Schwartz, P.J. 2010. Cascades or waterfalls, the cataracts of genetic screening are being opened on clinical cardiology (Editorial). Journal of the American College ofCardiology, 55(23): 2577-2579.

Schwartz, P.J. 2010. Efficacy of left cardiac sympathetic denervation has an unforeseen side effect: medicolegal complications. Heart Rhythm, 7: 1330-1332.

Schwartz, P.J. and Stramba-Badiale, M. 2010. Repolarization abnormalities in the newborn. Journal of Cardiovascular Pharmacology, 55(6): 539-543.

Schwartz, P.J., Spazzolini, C., Priori, S.G., Crotti, L., Vicentini, A., Landolina, M., Gasparini, M., Wilde, A.A.M., Knops, R.E., Denjoy, I., Toivenen, L., Monnig, G., Al-Fayyadh, M., Jordaens, L., Borggrefe, M., Holmgren, C., Brugada, P., De Roy, L.,Hohnloser, S.H. and Brink, P. 2010. Who are the long-QT syndrome patients who receive an implantable cardioverter-defibrillator and what happens to them? Circulation, 122: 1272-1282.

Seimon, T.A., Kim, M.-J., Blumenthal, A., Koo, J., Ehrt, S., Wainwright, H.C., Bekker, L.,Kaplan, G., Nathan, C., Tabas, I. and Russell, D.G. 2010. Induction of ER stress in macrophages of tuberculosis granulomas. PLoS One, 5(9). doi:10.1371/journal.pone.0012772. [IIDMM]

Selman, L., Higgingson, I., Agupio, G., dinat, N., Downing, J., Gwyther, L., Mashao, T., Mmoledi, K., Moll, A.P., Subuyira, L.M., Panajatovic, B. and Harding, R. 2009. Meeting information needs of patients with incurable progressive disease and their families in South Africa and Uganda: multicentre qualitative study. British Medical Journal, 338: b1326.

Setshedi, M., Wands, J.R. and de la Monte, S.M. 2010. Acetaldehyde adducts in alcoholic liver disease. Oxidative Medicine and Cellular Longevity, 3(3): 1-9.

Shey, M., Kongnyuy, E., Shang, J. and Wiysonge, C.S. 2009. A combination drug of abacavir-lamivudine-zidovudine (Trizivir (R)) for treating HIV infection and AIDS. Cochrane Database of Systematic Reviews, 3: CD005481. doi:10.1002/14651858.CD005481.pub2.

Shey, M., Randhawa, A., Bowmaker, M., Smith, E., Scriba, T.J., de Kock, M., Mahomed, H., Hussey, G.D., Hawn, T. and Hanekom, W.A. 2010. Single nucleotide polymorphisms in toll-like receptor 6 are associated with altered lipopeptide- and mycobacteria-induced interleukin-6 secretion. Genes and Immunity, 11: 561-572. [IIDMM]

Sierra-Madero, J., Di Perri, G., Wood, R. and Saag, M. 2010. Efficacy and safety of maraviroc versus efavirenz, both with zidovudine/lamivudine: 96-week results from the MERIT study. HIV Clinical Trials, 11(3): 125-132. [IIDMM]

Simek, M., Rida, W., Priddy, F.H., Pung, P., Carrow, E., Laufer, D.S., Lehrman, J.K., Boaz, M., Tarragona-Fiol, T., Miiro, G., Birungi, J., Pozniak, A., McPhee, D.A., Manigart, O., Karita, E., Inwoley, A., Jaoko, W., DeHovitz, J., Bekker, L., Pitisuttithum, P., Paris, R., Walker, L.M., Poignard, P., Wrin, T.,Fast, P.E., Burton, D. and Koff, W.C. 2009. Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm. Journal of Virology, 83(14): 7337-7348. [IIDMM]

Sinxadi, P., Van der Walt, J.-S., McIlleron, H., Badri, M., Smith, P.J., Dave, J.A., Levitt, N.S. and Maartens, G. 2010. Lack of association between stavudine exposure and lipoatrophy, dysglycaemia, hyperlactataemia and hypertriglyceridaemia: a prospective cross sectional study. AIDS Research and Theraphy, 7(23): 1-6.

Sliwa, K. and Mocumbi, A.O. 2010. Forgotten cardiovascular diseases in Africa. Clinical Research In Cardiology, 99: 65-74.

Sliwa, K., Blauwet, L., Tibazarwa, K., Libhaber, E., Smedema, J., Becker, A., McMurray, J., Yamac, H., Labidi, S., Struhman, I. and Hilfiker-Kleiner, D. 2010. Evaluation of bromocriptine in the treatment of acute severe peripartum cardiomyopathy: aproof-of-concept pilot study. Circulation, 121: 1465-1473. [IIDMM]

Sliwa, K., Carrington, M., Klug, E., Opie, L.H., Lee, G., Ball, J. and Stewart, S. 2010. Predisposing factors and incidence of newly diagnosed atrial fibrillation in an urban African community: insights from the Heart of Soweto Study. Heart, 96: 1878-1882.

Sliwa, K., Carrington, M., Mayosi, B.M., Zigiriadis, E., Mvungi, R. and Stewart, S. 2010. Incidence and characteristics of newly diagnosed rheumatic heart disease in Urban African adults: insights from the Heart of Soweto Study. EuropeanHeart Journal, 31: 719-727.

Sliwa, K., Hilfiker-Kleiner, D., Petrie, M.C., Mebazaa, A., Pieske, B., Buchmann, E., Regitz-Zagrosek, V., Schaufelberger, M., Tavazzi, L., van Veldhuisen, D.J., Watkins, H., Shah, A.J., Seferovic, P.M., Elkayam, U., Pankuweit, S., Papp, Z., Mouquet, F. andMcMurray, J. 2010. Current state of knowledge on aetiology, diagnosis, management, therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Working Group on peripartum cardiomyopathy. European Journal of Heart Failure, 12: 767-778.

Sloan, D., Dlamini, S., Paul, N. and Dedicoat, M. 2009. Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings. Cochrane Database of Systematic Reviews, 4: 1-40.

Smedema, J.P., Berlion, A.E. and Morkel, H. 2009. Mycardial infarcts in a patient with a single sided coronary ostium and interarterial course of the corcumflex artery: the role of multi-modality imaging. International Journal of Cardiology, 132(1): E42-E44.

Soares, A.P., Govender, L., Hughes, J., Mavakla, W., de Kock, M., Barnard, C., Pienaar, B., Janse van Rensburg, E., Jacobs, G., Stone, L., Abel, B., Scriba, T.J. and Hanekom, W.A. 2010. Novel application of Ki67 to quantify antigen-specific in vitro lymphoproliferation. Journal of Immunological Methods, 362: 43-50. [IIDMM]

Stein, E.A., Marais, A.D., Szamosi, T., Raal, F., Schurr, D., Urbina, E.M., Hopkins, P.N.,Karki, S., Xu, J., Misir, S. and Melino, M. 2010. Colesevelam hydrochloride: efficacy and safety in pediatric subjects with heterozygous familial hypercholesterolemia. Journal of Pediatrics, 156: 231-236.

Stepniewska, K., Ashley, E., Lee, S.J., Anstey, N., Barnes, K.I., Binh, T.Q., d'Alessandro, U., Day, N., De Vries, P.J., Dorsey, G., Guthmann, J., Mayxay, M., Newton, P., Olliaro, P., Osorio, L., Price, R.N., Rowland, M., Smithuis, F., Taylor, W.,Nosten, F. and White, N. 2010. In vivo parasitological measures of artemisinin susceptibility. Journal of Infectious Diseases, 201: 570-579.

Syed, F.F., Ntshekhe, M. and Mayosi, B.M. 2010. Cardiac thrombi in stress (Tako-Tsubo) cardiomyopathy: more than an apical issue? Mayo Clinic Proceedings, 85(9): 863-867.

Tena-Coki, N., Scriba, T.J., Peteni, N., Eley, B.S., Wilkinson, R.J., Andersen, P.,Hanekom, W.A. and Kampmann, B. 2010. CD4 and CD8 T-Cell responses to mycobacterial antigens in African children. American Journal ofRespiratory and Critical Care Medicine, 182: 120-129. [IIDMM]

Thompson, G.R., Barbir, M., Davies, D., Dobral, P., Gesinde, M., Livingston, M., Mandry, P., Marais, A.D., Matthews, S., Neuwirth, C., Pottle, A., le Roux, C., Scullard, D., Tyoer, C. andWatkins, S. 2010. Efficacy criteria and cholesterol targets for LDL apheresis. Atherosclerosis, 208: 317-321.

Tibazarwa, K. and Sliwa, K. 2010. Peripartum cardiomyopathy in Africa: challenges in diagnosis, prognosis, and therapy. Progress in Cardiovascular Diseases, 52: 317-325.

Tiffin, N., Meintjes, G., Ramesar, R.S., Bajic, V.B. and Rayner, B.L. 2010. Computational analysis of candidate disease genes and variants for salt-sensitive hypertension in indigenous Southern Africans. PLoS One, 5(9): e12989. [IIDMM]

Vaid, A., Ranjan, R., Smythe, W., Hoppe, H.C. and Sharma, P. 2010. PfPI3K, a phosphatidylinositol-3 kinase from Plasmodium falciparum, is exported to the host erythrocyte and is involved in hemoglobin trafficking. Blood, 115(12): 2500-2507.

van Der Plas, H. and Hardie, D.R. 2010. Herpes simplex virus 1 and 2:  a therapeutic approach. Southern African Journal of Epidemiology and Infection, 25(3): 5-9.

Van Schaik, N., Kranzer, K., Wood, R. and Bekker, L. 2010. Earlier HIV diagnosis – aremobile services the answer? SAMJ South African Medical Journal, 100(10): 671-674. [IIDMM]

Van Zyl Smit, R., Pai, M., Yew, W.W., Leung, C.C., Zumla, A., Bateman, E.D. andDheda, K. 2010. Global lung health: the colliding epidemics of tuberculosis, tobacco smoking, HIV and COPD. European Respiratory Journal, 35: 27-33.

Vezi, B.Z. 2009. Stroke reduction in patients with atrial fibrillation. Journal of the RoyalCollege of Physicians of Edinburgh, 39: 231-232.

Vivian, L.M.H., McLaughlin, S., Swanepoel, C.R. and Burch, V. 2010. Teaching biopsychosocial competence and the principles of primary health care (PHC) at the patient's bedside. African Journal of Health Professions Education, 2(2): 23-28.

Von Klemper, A. and Lecour, S. 2010. From bench to bedside: seeing the future of ischaemic post-conditioning as a novel cardioprotective therapy. SA Heart, 7(3): 166-171.

Waggie, Z., Hawkridge, A.J. and Hussey, G.D. 2010. Review of rotavirus studies in Africa: 1976-2006. Journal of Infectious Diseases, 202: S23-S33. [IIDMM]

Walensky, R.P., Wood, R., Ciaranello, A.L., Paltiel, A.D., Lorenzana, S.B., Anglaret, A.,Stoler, A.W. and Freedberg, K.A. 2010. Scaling up the 2010 World Health Organization HIV treatment guidelines in resource-limited settings: amodel-based analysis. PloS Medicine, 7(12): e1000382. [IIDMM]

Wallis, L., Papathanasopoulos, M., Lakhi, S., KARITA, A., KAMALI, A., KALEEBU, P., SANDERS, E., ANZALA, O., Bekker, L., STEVENS, G., RINKE DE WIT, T.F. AND STEVENS, W. 2010. Affordable in-house antiretroviral drug resistance assay with good performance in non-subtype B HIV-1. Journal of Virological Methods, 163: 505-508. [IIDMM]

Warner, J., Rosario, N., Potter, P.C., Wahn, U. and Baena-Cagnani, C.E. 2010. A Children's asthma charter (Editorial). Pediatric Allergy and Immunology, 21: 1-2.

Weber, I.B., Baker, L., Mnyaluza, J., Matjila, M., Barnes, K.I. and Blumberg, L. 2010. The burden of imported malaria in Gauteng Province. SAMJ South African Medical Journal, 100(5): 300-303.

Welschinger, R., Kew, M.C., Viana, R. and Badri, M. 2010. T1653 mutation in the enhancer II region of the hepatitis B virus genome in southern African blacks with hepatocellular carcinoma. European Journal of Gastroenterology & Hepatology, 22: 541-545.

Wijeratne, N. and Benatar, S.R. 2010. Ethical issues in laboratory medicine (Editorial). Journal of Clinical Pathology, 63(2): 97-98.

Wilkinson, K. and Wilkinson, R.J. 2010. Polyfunctional T cells in human tuberculosis. European Journal of Immunology, 40: 2139-2142. [IIDMM]

Wilson, D. and Meintjes, G. 2010. Timing of antiretroviral drugs during tuberculosis  therapy (Editorial). New England Journal of Medicine, 362(22): 2137.

Wood, R., Johnstone-Robertson, S., Uys, P., Hargrove, J., Middelkoop, K., Lawn, S.D.and Bekker, L. 2010. Tuberculosis transmission to young children in a South African community: modeling household and community infection risk. ClinicalInfectious Diseases, 51(4): 401-408. [IIDMM]

Wood, R., Liang, H., Wu, H., Middelkoop, K., Oni, T., Rangaka, M.X., Wilkinson, R.J.,Bekker, L. and Lawn, S.D. 2010. Changing prevalence of TB infection with increasing age in high TB burden townships in South Africa. InternationalJournal of Tuberculosis and Lung Disease, 14(4): 406-412. [IIDMM]

Yamac, H., Bultmann, I., Sliwa, K. and Hilfiker-Kleiner, D. 2010. Prolactin: a new therapeutic target in peripartum cardiomyopathy. Heart, 96: 1352-1357.

Yates, D., Jelsma, J.M. and Parker, R. 2010. The profile of people reporting with low back pain to a resource poor clinic in Cape Town. South African Journal ofPhysiotherapy, 66(2): 2-8.

Zipursky, S., Wiysonge, C.S. and Hussey, G.D. 2010. Knowledge and attitudes towards vaccines and immunization among adolescents in South Africa. Human Vaccines, 6(6): 455-461. [IIDMM]

Zumla, A., Huggett, J., Dheda, K., Green, C., Kapata, N. and Mwaba, P. 2010. Trials and tribulations of an African-led research and capacity development programme: the case for EDCTP investments. Tropical Medicine & International Health, 15(4): 489-494.

ZuWallack, R., De Salvo, M.C., Kaelin, T. and Bateman, E.D. 2010. Efficacy and safety of ipratropium bromide/albuterol delivered via Respimat (R) inhaler versus MDI. Respiratory Medicine, 104: 1197-1188.

Zvada, S.P., Van der Walt, J.-S., Smith, P.J., Fourie, P.B., Roscigno, G., Mitchison, D., Simonsson, U. and McIlleron, H. 2010. Effects of four different meal types on the population pharmacokinetics of single-dose rifapentine in healthy male volunteers. Antimicrobial Agents and Chemotherapy, 54(8): 3390-3394.

IAA – Albertina and Walter Sisulu Institute of Ageing in Africa

IIDMM – Institute of Infectious Disease and Molecular Medicine

IIDRG – Medical Research Council/UCT Immunology of Infectious Diseases Research Unit

 
 

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