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Research Output

Chapters in books

Artz, L.M. and Pithey, B. 2010. The expert witness and the J88 in criminal proceedings. In K. Joyner (ed.), Aspects of Forensic Medicine. An Introduction for Healthcare Professionals, pp. 1-22. South Africa: Juta & Co. Ltd. ISBN 9780702186585.

Hendry, I. 2010. Forensic care in sexual offences. In K. Joyner (ed.), Aspects of Forensic Medicine. An Introduction for Healthcare Professionals, pp. 23-44. South Africa: Juta & Co. Ltd. ISBN 9780702186585.

Martin, L.J. 2010. Emergency care of the sexual assault survivor. In A. Nicol and E. Steyn (eds), Handbook of Trauma, pp. 345-354. Second edition. South Africa: Oxford University Press Southern Africa (Pty) Ltd. ISBN 9780195987478.

Martin, L.J. 2010. Forensic wound identification. In K. Joyner (ed.), Aspects of Forensic Medicine. An Introduction for Healthcare Professionals, pp. 101-115. South Africa: Juta & Co. Ltd. ISBN 9780702186585.

Potter, P.C. and Foot, L. 2010. Latex allergy. In R.J. Green, C. Motala and P.C. Potter (eds), ALLSA Handbook of Practical Allergy, pp. 147-161. Third Edition. South Africa: Allergy Society of South Africa. ISBN 9780620480864.

Potter, P.C. and Weinberg, E.G. 2010. Allergen immunotherapy. In R.J. Green, C. Motala and P.C. Potter (eds), ALLSA Handbook of Practical Allergy, pp. 191-200. Third Edition. South Africa: Allergy Society of South Africa. ISBN 9780620480864.

Potter, P.C., Green, R. and Haus, M. 2010. Prevention of allergic disease. In R.J. Green, C. Motala and P.C. Potter (eds), ALLSA Handbook of Practical Allergy, pp. 212-217. Third Edition. South Africa: Allergy Society of South Africa. ISBN 9780620480864.

Potter, P.C., Hawarden, D. and Karabus, S. 2010. Drug allergy. In R.J. Green, C. Motala and P.C. Potter (eds), ALLSA Handbook of Practical Allergy, pp. 130-146. Third Edition. South Africa: Allergy Society of South Africa. ISBN 9780620480864.

Williamson, C. and Martin, D.P. 2010. HIV-1 genetic diversity. In S.S. Abdool Karim and Q. Abdool Karim (eds), HIV/AIDS in South Africa, pp. 117-126. Second Edition. Cape Town: Cambridge University Press. ISBN 9780521147934. [IIDMM]

Articles in Peer-reviewed Journals

Abel, B., Tameris, M.D., Mansoor, N., Gelderbloem, S., Hughes, J., Abrahams, D.A., Makhethe, L., Erasmus, M., de Kock, M., Van der Merwe, L., Hawkridge, A., Veldsman, A., Hatherill, M., Schirru, G., PAU, m., Hendricks, J., weverling, g., goudsmit, j., sizemore, d., McClain, J., Goetz, M.A., gearhart, j., Mahomed, H., Hussey, G.D., Sadoff, J.C. andHanekom, W.A. 2010. The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults. American Journal of Respiratoryand Critical Care Medicine, 181: 1407-1417. [IIDMM]

Abera, A., Sales, K., Catalano, R.D., Katz, A.A. and Jabbour, H. 2010. EP2 receptor mediated cAMP release is augmented by PGF2 activation of the FP receptor via the calcium-calmodulin pathway. Cellular Signalling, 22: 71-79. [IIDMM]

Abrahams, A., Parker, M.I. and Prince, S. 2010. The T-box transcription factor Tbx2: its role in development and possible implication in cancer. IUBMB Life, 62(2): 92-102. [IIDMM][OCRG]

Achilonu, I.A., Gildenhuys, S., Fisher, L., Burke, J., Fanucchi, S., Sewell, B.T.,Fernandes, M.A. and Dirr, H.W. 2010. The role of a topologically conserved isoleucine in glutathione transferase structure, stability and function. Acta Crystallographica Section F – StructuralBiology and Crystallization Communications, F66: 776-780. [IIDMM]

Akif, M., Georgiadis, D., Mahajan, A., Dive, V., Sturrock, E.D., Elwyn Isaac, R. andAcharya, K.R. 2010. High-resolution crystal structures of drosophila melanogaster angiotensin-converting enzyme in complex with novel inhibitors and antihypertensive drugs. Journal of Molecular Biology, 400: 502-517. [IIDMM]

Akif, M., Ntai, I., Sturrock, E.D., Elwyn Isaac, R., Bachmann, B.O. and Acharya, K.R. 2010. Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster. Biochemical and Biophysical Research Communications, 398: 532-536. [IIDMM]

Albuquerque, L.C., Martin, D.P., Avila, A.C. and Inoue-Nagata, A. 2010. Characterization of tomato yellow vein streak virus, a begomovirus from Brazil. VirusGenes, 40: 140-147. [IIDMM]

Allie, N., Keeton, R., Court, N., Abel, B., Fick, L., Vasseur, V., Vacher, R., Olleros, M., Drutskaya, M.S., Guler, R., Nedospasov, S., Garcia, I., Ryffel, B., Quesniaux, V. andJacobs, M. 2010. Limited role for lymphotoxin  in the host immune response to Mycobacterium tuberculosis. Journal of Immunology, 185: 4292-4301. [IIDMM]

Anthony, C., corradi, h., Schwager, S.L.U., Redelinghuys, P., Georgiadis, D., Dive, V.,Acharya, K.R. and Sturrock, E.D. 2010. The N domain of human angiotensin-I-converting enzyme. The role of N-glycosylation and the crystal structure in complex with an N domain-specific phosphinic inhibitor, RXP407*. Journal of Biological Chemistry, 285(46): 35685-35693. [IIDMM]

Arendse, R., Gcelu, A., Scott, C., Beighton, P. and Kalla, A.A. 2010. Do the radiographic features of joint destruction in tophaceous gout imply a different pathophysiology to that of rheumatoid and psoriatic arthritis? Clinical Rheumatology, 29: 1181-1183.

Auerswald, L., Pape, C., Stubing, D., Lopata, A.L. and Meyer, B. 2009. Effect of short-term starvation of adult Antarctic krill, Euphausia superba, at the onset of summer. Journal of Experimental Marine Biology and Ecology, 381(1): 47-56.

Baatjies, R., Meijster, T., Lopata, A.L., Sander, I., Raulf-Heimsoth, M., Heederik, D. andJeebhay, M.F. 2010. Exposure to flour dust in South African supermarket bakeries: modeling of baseline measurements of an intervention study. Annals of Occupational Hygiene, 54(3): 309-318.

Bere, A., Denny, L.A., Burgers, W. and Passmore, J.S. 2010. Polyclonal expansion of cervical cytobrush-derived T cells to investigate HIV-specific responses in the female genital tract. Immunology, 130: 23-33. [IIDMM]

Bere, A., Denny, L.A., Hanekom, W.A., Burgers, W. and Passmore, J.S. 2010. Comparison of polyclonal expansion methods to improve the recovery of cervical cytobrush-derived T cells from the female genital tract of HIV-infected women. Journal ofImmunological Methods, 354(1-2): 68-79. [IIDMM]

Bhaijee, F., Wainwright, H.C., Meintjes, G., Wilkinson, R.J., Todd, G., de Vries, E. andPepper, D.J. 2010. Warfarin-induced skin necrosis in HIV-infected patients with tuberculosis and venous thrombosis. SAMJ South African Medical Journal, 100(6): 372-377. [IIDMM]

Billingsley, G., Bin, J., Fieggen, K., Duncan, J.L., Gerth, C., Ogata, K., Wodak, S.S., Traboulsi, E.I., Fishman, G.A., Paterson, A., Chitayat, D., Knueppel, T., Millam, J.M.,Mitchell, G.A., Deveault, C. and Heon, E. 2010. Mutations in chaperonin-like BBS genes are a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Journal of Medical Genetics, 47: 453-463.

Blokhuis, M., Pietersen, G.E., Goldberg, P.A., Algar, U., van der Merwe, L., Mbatani, N.,Vorster, A.A. and Ramesar, R.S. 2010. Lynch syndrome: the influence of environmental factors on extracolonic cancer risk in hMLH1 c.C1528T mutation carriers and their mutation-negative sisters. Familial Cancer, 9: 357-363. [IIDMM]

Blum, R., Gupta, R., Burger, P.E., Ontiveros, C.S., SALM, S.N., Xiong, X., Kamb, A., Wesche, H., Marshall, L., Cutler, G., Wang, X., Zavadil, J., Moscatelli, D. and Wilson, E.L. 2010. Molecular signatures of the primitive prostate stem cell niche reveal novel mesenchymal-epithelial signaling pathways. PLoSOne, 5(9): e13024.

Boehme, C., Nabeta, P., Hillermann, D., Nicol, M.P., Shenai, S., Krapp, F., Allen, J., Tahirli, R., Blakemore, R., Rustomjee, r., Milovic, A., Jones, M., O'Brien, S.M., Persing, D.H., Ruesch-Gerdes, S., Gotuzzo, E., Rodrigues, C., Alland, D. and Perkins, M.D. 2010. Rapid molecular detection of tuberculosis and Rifampin resistance. New England Journal of Medicine, 363(11): 1005-1015. [IIDMM]

Borck, G., Beighton, P., Wilhelm, C., Kohlhase, J. and Kubisch, C. 2010. Arterial rupture in classic Ehlers-Danlos syndrome with COL5A1 mutation. AmericanJournal of Medical Genetics PartA, 152: 2090-2093.

Boyles, T.H. and Joska, J. 2009. The behaviourally disturbed patient with HIV/AIDS. Southern African Journal of HIV Medicine, 35: 28-29.

Brattstrom, A., Schapowal, A., Kamal, M.A., Maillet, I., Ryffel, B. and Moser, R. 2010. The plant extract Isatis tinctoria L. extract (ITE) inhibits allergen-induced airway inflammation and hyperreactivity in mice. Phytomedicine, 17: 551-556.

Briddon, R., Heydarnejad, J., Khosrowfar, F., Massumi, H., Martin, D.P. and Varsani, A. 2010. Turnip curly top virus, a highly divergent geminivirus infecting turnip in Iran. Virus Research, 152: 169-175. [IIDMM]

Briddon, R., Martin, D.P., Owor, B.E., Donaldson, L.E., Markam, P.G., Greber, R.S. andVarsani, A. 2010. A novel species of mastrevirus (family Geminiviridae) isolated from Digitaria didactyla grass from Australia. Archives ofVirology, 155: 1529-1534. [IIDMM]

Carlos, D., Fremond, C., Samarina, A. and Ryffel, B. 2009. Histamine plays an essential regulatory role in lung inflammation and protective immunity in the acute phase of Mycobacterium tuberculosisinfection. Infection and Immunity, 77(12): 5359-5368.

Carvalho, S.E.S., Martin, D.P., Oliveira, L.M., Ribeiro, B.M. and Nagata, T. 2010. Comparative analysis of American Dengue virus type 1 full-genome sequences. Virus Genes, 40: 60-66. [IIDMM]

Cashmore, T., Peter, J., Van Zyl Smit, R., Semple, P.L., Maredza, A., Meldau, R.,Zumla, A., Nurse, B. and Dheda, K. 2010. Feasibility and diagnostic utility of antigen-specific interferon-responses for rapid immunodiagnosis of tuberculosis using induced sputum. PLoS One, 5(4): e10389.

Chapman, R.E., Chege, G., Shephard, E.G., Stutz, H. and Williamson, A.-L. 2010. Recombinant Mycobacterium bovis BCG as an HIV vaccine vector. Current HIVResearch, 8: 282-298. [IIDMM]

Chatterjee, K., Dandara, C., Gyllensten, U., van der Merwe, L., Galal, U., Hoffman, M.andWilliamson, A.-L. 2010. A fas gene polymorphism influences herpes simplex virus type 2 infection in South African women. Journal of MedicalVirology, 82: 2082-2086. [IIDMM]

Chatterjee, K., Dandara, C., Hoffman, M. and Williamson, A.-L. 2010. CCR2-V641 polymorphism is associated with increased risk of cervical cancer but not with infection or pre-cancerous lesions in African women. BMC Cancer, 10(278). http://www.biomedcentral.com/1471-2407/10/278. [IIDMM]

Chellan, P., Shunmoogam-Gouder, N., Hendricks, D.T., Gut, J., Rosenthal, P.J., Lategan, C., Smith, P.J., Chibale, K. and Smith, G.S. 2010. Synthesis, structure and in vitro biological screening of palladium(II) complexes of functionalised salicylaldimine thiosemicarbazones as antimalarial and anticancer agents. European Journal of Inorganic Chemistry, 2010: 3520-3528. [IIDMM]

Connell, T.G., Davies, M., Johannisen, C.F., Wood, K.A., Pienaar, S.M., Wilkinson, K., Wilkinson, R.J., Zar, H.J., Beatty, D.W., Nicol, M.P., Curtis, N. and Eley, B.S. 2010. Reversion and conversion of Mycobacterium tuberculosisIFN-γELISpot results during anti-tuberculosis treatment in HIV-infection children. BMCInfectious Diseases, 10:138. [Online]. http://www.biomedcentral.com/1471-2334/10/138. [IIDMM]

Corcoran, C., Hardie, D.R., Yeats, J. and Smuts, H. 2010. Genetic variants of Human Parvovirus B19 in South Africa: co-circulation of three genotypes and Identification of a novel subtype of Genotype 1. Journal of Clinical Microbiology, 48(1): 137-142.

Coutts, N. and Harley, E.H. 2009. Comparative population genetics of the German shepherd dog in South Africa. South African Journal of Science, 105(3-4): 132-135.

Dalal, S., Holmes, M.D. and Ramesar, R.S. 2010. Advancing public health genomics in Africa through prospective cohort studies. Journal of Epidemiology andCommunity Health, 64(7): 585-586. [IIDMM]

Dalvie, S., Horn, N., Nossek, C., van der Merwe, L., Stein, D.J. and Ramesar, R.S. 2010. Psychosis and relapse in bipolar disorder are related to GRM3, DAOA, and GRIN2B genotype. African Journal of Psychiatry, 13: 297-301. [IIDMM]

de Andrade, M.C.C., Affonso, R., Fernandes, F.B., Febba, A.C., de Silva, I.D.C.G., Stella, R.C.R., Marson, O., Jubilut, G.N., Hirata, I.Y., Carmona, A., corradi, h.,Acharya, K.R., Sturrock, E.D. and Casarini, D.E. 2010. Spectroscopic and structural analysis of somatic and N-domain angiotensin I-converting enzyme isoforms from mesangial cells from Wistar and spontaneously hypertensive rats. International Journal of Biological Macromolecules, 47: 238-243. [IIDMM]

De Wit, E., Delport, W., Rugamika, C.E., Meintjes, A., Moller, M., Van Helden, P.,Seoighe, C. and Hoal, E. 2010. Genome-wide analysis of the structure of the South African coloured population in the Western Cape. Human Genetics, 128: 145-153.

Delport, W., Scheffler, K.S. and Seoighe, C. 2009. Models of coding sequence evolution. Briefings in Bioinformatics, 10(1): 97-109.

Dewals, B., Hoving, J., Horsnell, W. and Brombacher, F. 2010. Control of Schistosoma mansoni egg-induced inflammation by IL-4-responsive CD4+CD25-CD103+Foxp3-cells is IL-10-dependent. European Journal of Immunology, 40(10): 2837-2847. [IIDMM][IIDRU]

Dewals, B., Marillier, R., Hoving, J., Leeto, M., Schwegmann, A. and Brombacher, F. 2010. Il-4Rα-independent expression of Mannose receptor and Ym1 by macrophages depends on their IL-10 responsiveness. PloSNeglected TropicalDiseases, 4(5): e689. doi:10.1371/journal.pntd.0000689. [IIDMM] [IIDRU]

Dheda, K., Davids, V., Lenders, L., Roberts, T., Meldau, R., Ling, D., Brunet, L., Van Zyl Smit, R., Peter, J., Green, C., Badri, M., Sechi, L.A., Sharma, S.K., Hoelscher, M., Dawson, R., Whitelaw, A.C., Blackburn, J., Pai, M.and Zumla, A. 2010. Clinical utility of a commercial LAM-ELISA assay for TB diagnosis in HIV-infected patients using urine and sputum samples. PLoS One, 5(3): e9848. doi:10.1371/journal.pone.0009848. [IIDMM]

Dimitropoulos, N., Papakyriakou, A., Dalkas, G.A., Sturrock, E.D. and Spyroulias, G.A. 2010. A computational approach to the study of the binding mode of dual ACE/NEP inhibitors. Journal of Chemical Information and Modeling, 50: 388-396. [IIDMM]

Duah, N., Miles, D.J.C., Whittle, H.C. and Conway, D.J. 2010. Acquisition of antibody isotypes against Plasmodium falciparum blood stage antigens in a birth cohort. Parasite Immunology, 32: 125-134.

Dunn, R.N. 2010. The medical management of spinal tuberculosis. SA OrthopedicJournal, 9(1): 37-41.

Dunn, R.N. and Van Der Spuy, D. 2010. Rugby and cervical spine injuries – hasanything changed? A 5-year review in the Western Cape. SAMJ South African MedicalJournal, 100(4): 235-238.

Eklund, C., Zhou, T., Dillner, J., Williamson, A.-L. and WHO Human PapillomavirusNetwork. 2010. Global proficiency study of human papillomavirus genotyping. Journal of Clinical Microbiology, 48(11): 4147-4155. [IIDMM]

Evans, J. and Segal, H. 2010. Novel multiplex allele-specific PCR assays for the dection of resistance to second-line drugs in Mycobacterium tuberculosis. Journal ofAntimicrobial Chemotherapy, 65: 897-900. [IIDMM]

Firnhaber, C., Zungu, K., Levin, S., Michelow, P., Montaner, D., McPhail, P., Williamson, A.-L., Allan, B.R., Van Der Horst, C., Rinas, A. and Sanne, I. 2009. Diverse and high prevalence of human papillomavirus associated with a significant high rate of cervical dysplsia in human immunodeficiency virus-infected women in Johannesburg, South Africa. Acta Cytologica, 53(1): 10-17. [IIDMM]

Fletcher, H., Keyser, A.T., Bowmaker, M., Sayles, P., Kaplan, G., Hussey, G.D., Hill, A.V.S. and Hanekom, W.A. 2009. Transcriptional profiling of mycobacterial antigen-induced responses in infants vaccinated with BCG at birth. BMCMedical Genomics, 2:10. [Online]. http://www.biomedcentral.com/1755-8794/2/10. [IIDMM]

Folefoc, A., Fromme, B.J., Katz, A.A. and Flanagan, C. 2010. South African mutations of the CCR5 coreceptor for HIV modify interaction with chemokines and HIV envelope protein. JAIDS – Journalof Acquired Immune Deficiency Syndromes, 54(4): 352-359. [IIDMM]

Freitas, A., Alves, J.C., Victoni, T., Secher, T., Lemos, H.P., Sonego, F., Cunha, F.Q.andRyffel, B. 2009. IL-17 Receptor signalling is required to control polymicrobial sepsis. Journal of Immunology, 182(12): 7846-7854.

Gammon, D.W., Steenkamp, D.J., Mavumengwana, V., Marakalala, M., Mudzunga, T.T.,Hunter, R. and Munyololo, M. 2010. Conjugates of plumbagin and phenyl-2-amino-1-thioglucoside inhibit MshB, a deacetylase involved in the biosynthesis of mycothiol. Bioorganic & Medicinal Chemistry, 18: 2501-2514.

Gaujoux, R. and Seoighe, C. 2010. A flexible R package for nonnegative matrix factorization. BMC Bioinformatics, 11:367. [Online]. http://www.biomedcentral.com/1471-2105/11/367.

George, D., Watermeyer, G., Levin, D., Epstein, D., Ross, I.L., Scholz, U., Setshedi, M., Locketz, M.L., Dittrich, C., Shaw, J.M. and Krige, J.E.J. 2010. Composite adrenal phaeochromocytoma-ganglioneuroma causing watery diarrhoea, hypokalaemia and achlorhydria syndrome. European Journal of Gastroenterology &Hepatology, 22(5): 632-634.

George, J.T., Millar, R.P. and Anderson, R.A. 2010. Hypothesis:Kisspeptin mediates male hypogonadism in obesity and type 2 diabetes. Neuroendocrinology, 91: 302-307.

Ghebremariam, Y., Engelbrecht, G.H.C., Tyler, M., Lotz, Z., Govender, D., Kotwal, G.J.and Kahn, D. 2010. Vaccinia virus complement control protein (VCP) improves kidney structure and function following ischemia/reperfusion injury in rats. Journal of Surgical Research, 159: 747-754.

Gildenhuys, S., Dobreva, M., Kinsley, N., Sayed, Y., Burke, J., Pelly, S., Gordon, G.P.,Sayed, M., Sewell, B.T. and Dirr, H.W. 2010. Arginine 15 stabilizes an SNAr reaction transition state and the binding of anionic ligands at the active site of human glutathione transferase A1-1. Biophysical Chemistry, 146: 118-125. [IIDMM]

Graham, A.P., Martin, D.P. and Roye, M.E. 2010. Molecular characterization and phylogeny of two begomoviruses infecting Malvastrum americanum in Jamaica: evidence of the contribution of inter-species recombination to the evolution of malvaceous weed-associated begomoviruses from the Northern Caribbean. Virus Genes, 40: 256-266. [IIDMM]

Gray, C., Mlotshwa, M., Riou, C., Mathebula, T., Rosa, D., Mashishi, T., Seoighe, C., Ngandu, N., van Loggerenberg, F., Morris, L., Mlisana, K., Williamson, C. and Karim, S. 2009. Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set point. Journal of Virology, 83(1): 470-478. [IIDMM]

Green, V.A., Munshi, S.U., Marakalala, M. and Mourao, M.M. 2010. Molecular mechanisms of viral infection and propagation: an overview of the second advanced summer school in Africa. IUBMB Life, 62(8): 573-583.

Greenberg, J., Roberts, L.J., Bruwer, Z., Schoeman, M., Loggenberg, K. and Loubser, F. 2010. Delivery of an ophthalmic genetic service in South Africa. SA Ophthalmology Journal, 1: 14-19. [IIDMM]

Haarburger, D. and Pillay, T. 2010. Discovery proteomics: application to HIV infection. Journal of Clinical Pathology, 63(4): 285.

Hanekom, W.A., Lawn, S.D., Dheda, K. and Whitelaw, A.C. 2010. Tuberculosis research update. Tropical Medicine & International Health, 15(8): 981-989. [IIDMM]

Hardie, D.R. 2010. Human y-herpesviruses:  a review of 2 divergent paths to oncogenesis. Transfusion and Apheresis Science, 42: 177-183.

Harley, E.H., Knight, M.H., Lardner, C., Woodling, B. and Gregor, M. 2009. The Quagga project: progress over 20 years of selective breeding. South AfricanJournalof Wildlife Research, 39: 155-163.

Heckmann, J.M., Pillay, K., Hearn, A.P. and Kenyon, C. 2010. Polymyositis in African HIV-infected subjects. Neuromuscular Disorders, 20: 735-739.

Hiller, N.L., Ahmed, A., Powell, E. and Martin, D.P. 2010. Generation of genic diversity among Streptococcus pneumoniaestrains via horizontal gene transfer during a chronic polyclonal pediatric infection. PLoS Pathogens, 6(9): e1001108. doi:10.1371/journal.ppat.1001108. [IIDMM]

Holder, B., Miles, D.J.C., Kaye, S., Crozier, S. et al. 2010. Epstein-Barr virus but not cytomegalovirus is associated with reduced vaccine antibody responses in Gambian infants. PLoS One, 5(11): e14013. doi:10.1371/journal.pone.0014013.

Horsnell, W. and Brombacher, F. 2010. Genes associated with alternatively activated macrophages discretely regulate helminth infection and pathogenesis in experimental mouse models. Immunobiology, 215(10): 704-708. [IIDMM][IIDRU]

Hunig, T., Luhder, F., Elflein, K., Gogishvili, T., Frohlich, M., Guler, R., Cutler, A. andBrombacher, F. 2010. Cd28 and IL-4: two heavyweights controlling the balance between immunity and inflammation. Medical Microbiology andImmunology, 199(3): 239-246. [IIDMM][IIDRU]

Hunter, S., Apweiler, R., Attwood, T.K., Bairoch, A., Bateman, A., Binns, P., Bork, P., Das, U., Daugherty, L., Duquenne, L., Finn, R.D., Gough, J., Haft, D., Hulo, N., Kahn, D., Kelly, E., Laugraud, A., Letunic, I., Lonsdale, D., Lopez, R., Madera, M., Maslen, J., McAnulla, C., McDowall, J., Mistry, J., Mitchell, A., Mulder, N.J., Natale, D., Orengo, C., Quinn, A.F., Selengut, J.D., Sigrist, C.J.A., Thimma, M., Thomas, P.D., Valentin, F.,Wilson, D., Wu, C.H. and Yeats, C. 2009. InterPro: the integrative protein signature database. Nucleic Acids Research, 36(S1): D211-D215. [IIDMM]

Jarvis, J.N., Wainwright, H.C., Harrison, T., Rebe, K. and Meintjes, G. 2010. Pulmonary crptococcosis misdiagnosed as smear-negative pulmonary tuberculosis with fatal consequences. International Journal of Infectious Diseases, 14S: e310-e312.

Joska, J., Combrinck, M.I., Valcour, V.G., Hoare, J., Leisegang, F., Mahne, A.C., Myer, L. and Stein, D.J. 2010. Association between apolipoprotein E4 genotype and human immunodefiency virus-associated dementia in younger adults starting antiretroviral therapy in South Africa. Journal of Neurovirology, 16: 377-383.

Joubert, M.K., Kinsley, N., Capovilla, A., Sewell, B.T., Jaffer, M.A. and Khati, M. 2010. Amodeled structure of an aptamer-gp120 complex provides insight into the mechanism of HIV-1 neutralization. Biochemistry, 49: 5880-5890. [IIDMM]

Kagina, B., Abel, B., Scriba, T.J., Hughes, E.J., Keyser, A.T., Soares, A.P., Gamieldien, H., Sidibana, M., Hatherill, M., Gelderbloem, S., Mahomed, H., Hawkridge, A., Hussey,G.D., Kaplan, G. and Hanekom, W.A. 2010. Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after Bacillus Calmette-Guerin vaccination of newborns. AmericanJournal of Respiratory and Critical Care Medicine, 182: 1073-1079. [IIDMM]

Kanapin, A.A., Mulder, N.J. and Kuznetsov, V.A. 2010. Projection of gene-protein networks to the functional space of the proteome and its application to analysis of organism complexity. BMC Genomics, 11(Suppl 1): S4. doi: 10.1186/1471-2164-11-S1-S4. [IIDMM]

Kaschula, C.H., Hunter, R. and Parker, M.I. 2010. Garlic-derived anticancer agents: structure and biological activity of ajoene. Biofactors, 36(1): 78-85. [IIDMM] [OCRG]

Keddy, K., Smith, A.M., Sooka, A., Ismail, H. and Oliver, S.P. 2010. Fluoroquinolone-resistant typhoid, South Africa. Emerging Infectious Diseases, 16(5): 879-880

Kenyon, C., Pillay, K. and Heckmann, J.M. 2010. Beware of 'normal' creatine kinase levels in HIV-associated polmyositis. SAMJ South African Medical Journal, 100(3): 156-157.

Kerrigan, A. and Brown, G.D. 2009. C-type lectins and phagocytosis. Immunobiology, 214: 562-575.

Khutlang, R., Krishnan, S., Dendere, R., Whitelaw, A.C., Veropoulos, K., Learmonth, G.M. andDouglas, T.S. 2010. Classification of Mycobacterium tuberculosis in images of ZN-stained sputum smears. IEEE Transactions on InformationTechnology in Biomedicine, 14(4): 949-957.

Khutlang, R., Krishnan, S., Whitelaw, A.C. and Douglas, T.S. 2010. Automated detection of tuberculosis in Ziehl-Neelsen-stained sputum smears using two one-class classifiers. Journal of Microscopy – Oxford, 237(1): 96-102.

Kim, M.-J., Wainwright, H.C., Locketz, M.L., Bekker, L., Walther, G., Dittrich, C., Visser, A., Wang, W., Hsu, F.-F., Weihart, U., Tsenova, L., Kaplan, G. and Russell, D.G. 2010. Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism. EMBO Molecular Medicine, 2(7): 258-274. [IIDMM]

Kirstein, F., Horsnell, W., Nieuwenhuizen, N., Ryffel, B., Lopata, A.L. and Brombacher, F. 2010. Anisakis pegreffi-induced airway hyperresponsiveness is mediated by gamma interferon in the absence of interleukin-4 receptor alpha responsiveness. Infection and Immunity, 78(9): 4077-4086. [IIDMM][IIDRU]

Kirsten-Sardinha, K., Horsnell, W., Kuperman, D.A., Huang, X., Erle, D., Lopata, A.L.and Brombacher, F. 2010. Expression of IL-4 receptor  on smooth muscle cells is not necessary for development of experimental allergic asthma. Journalof Allergy and Clinical Immunology, 126: 347-354. [IIDRU]

Kongnyuy, E., Wiysonge, C. and Shey, M. 2009. A systematic review of randomized controlled trials of prenatal and postnatal vitamin A supplementation of HIV-infected women. International Journal of Gynecology & Obstetrics, 104: 5-8.

Kraus, M.H., Parrish, N.F., Shaw, K.S., Decker, J.M., Keele, B.F., Salazar-Gonzalez, J.F., Grayson, T., McPherson, D.T., Ping, L.H., Anderson, J.A., Swanstrom, R.,Williamson, C., Shaw, G.M. and Hahn, B.E. 2010. A rev1-vpu polymorphism unique to HIV-1 subtype A and C strains impairs envelopeglycoprotein expression from rev-vpu-env cassettes and reduces virion infectivity inpseudotyping assays. Virology, 397: 346-357. [IIDMM]

Kyriakou, C., Canals, C., Finke, J., Kobbe, G., Harousseau, J.-L., Kolb, H.J., Novitzky, N., Goldstone, A.H., Sureda, A. and Schmitz, N. 2009. Allogeneic stem cell transplantation is able to induce long-term remissions in angioimmunoblastic T-cell lymphoma: aretrospective study from the Lymphoma Working Party of the European Group for Blood and Marrow Transplantation. Journal of Clinical Oncology, 27(24): 3951-3958.

Lefeuvre, P., Martin, D.P., Harkins, G.W., Lemey, P., Gray, A., Meredith, S., Lakay, F.,Monjane, A., Lett, J.-M., Varsani, A. and Heydarnejad, J. 2010. The spread of tomato yellow leaf curl virus from the Middle East to the world. PLoS Pathogens, 6(10): e1001164. http://www.plospathogens.org. [IIDMM]

Lewis, D.A. 2010. The Gonococcus fights back: is the time a knock out? SexuallyTransmitted Infections, 86: 415-421.

Li, D., Dandara, C. and Parker, M.I. 2010. The 341C/T polymorphism in the GSTP1 gene is assoicated with increased risk of oesophageal cancer. BMC Genetics, 11:47. [Online] http://www.biomedcentral.com/1471-2156/11/47.[IIDMM][OCRG]

Liebenberg, L., Adedeji, A., Martin, D.P., Gumbi, P., Denny, L.A. and Passmore, J.S. 2010. CD57 expression by T cells in the female genital tract of HIV-zx1 infected women. Clinical Immunology, 135(1): 137-145. [IIDMM]

Loyse, A., Wainwright, H.C., Jarvis, J.N., Bicanic, T., Rebe, K., Meintjes, G. andHarrison, T. 2010. Histopathology of the arachnoid granultions and brain in HIV-associated cryptococcal meningitis: correlation with cerebrospinal fluid pressure. AIDS, 24: 405-410.

Lynch, A.G., Tanzer, F.L., Fraser, M.J., Shephard, E.G., Williamson, A.-L. and Rybicki, E.P. 2010. Use of the piggyBac transposon to creat HIV-1 gag transgenic insect cell lines for continuous VLP production. BMC Biotechnology, 10:30. [Online] http://biomedcentral.com/1472-6750/10/30. [IIDMM]

Mall, A.S., Tyler, M., Ho, S.B., Krige, J.E.J., Kahn, D., Spearman, W., Myer, L. andGovender, D. 2010. The expression of MUC mucin in cholangiocarcinoma. Pathology Research and Practice, 206(12): 805-809.

Mann, g., B Squire, B., Bissell, K., Eliseev, P., Du Toit, E., Hesseling, A., Nicol, M.P.,Detjen, A. and Kritski, A. 2010. Beyond accuracy: creating a comprehensive evidence base for tuberculosis diagnostic tools. International Journal ofTuberculosis and Lung Disease, 14(12): 1518-1524. [IIDMM]

Marais, S., Pepper, D.J., Marais, B. and Torok, M.E. 2010. HIV-associated tuberculous meningitis – diagnosticand therapeutic challenges. Tuberculosis, 90: 367-374.

Marillier, R., Bogale, T., Dewals, B., Leeto, M., Barkhuizen, M., Govender, D., Kellaway, L.A., Horsnell, W. and Brombacher, F. 2010. IL-4R-responsive smooth muscle cells increase intestinal hypercontractility and contribute to resistance during acute Schistosomiasis. American Journal of Physiology –Gastrointestinaland Liver Physiology, 298(6): G943-G951. [IIDRU]

Martin, D.P., Lemey, P., Lott, M., Moulton, V., Posada, D. and Lefeuvre, P. 2010. RDP3: a flexible and fast computer program for analyzing recombination. Bioinformatics, 26: 2462-2463. [IIDMM]

Martineau, A., Leandro, A.C.C.S., Anderson, S., Newton, S., Wilkinson, K., Nicol, M.P., Pienaar, S., Skolimowska, K., Rocha, M.A., Rolla, V.C., Levin, M., Davidson, R., Bremner, S.A., Griffiths, C., Eley, B.S., Bonecini-Almeida, M.G. and Wilkinson, R.J. 2010. Association between Gc genotype and susceptibility to TB is dependent on vitamin D status. European Respiratory Journal, 35: 1106-1112. [IIDMM]

Mbulawa, Z., Marais, D.J., Johnson, L., Boulle, A.M., Coetzee, D.J. and Williamson, A.-L. 2010. Influence of human immunodeficiency virus and CD4 count on the prevalence of human papillomavirus in heterosexual couples. Journal of General Virology, 10(91): 3023-3031. [IIDMM]

Meyer, B., Auerswald, L., Siegel, V., Spahic, S., Pape, C., Fach, B.A., Teschke, M.,Lopata, A.L. and Fuentes, V. 2010. Seasonal variation in body composition, metabolicactivity, feeding, and growth of adult krill Euphausia superba in the Lazarev Sea. Marine Ecology-Progress Series, 398: 1-18.

Mhlongo, S., Magooa, P., Muller, E. andLewis, D.A. 2010. Etiology and STI/HIV coinfections among patients with urethral and vaginal discharge syndromes in South Africa. Sexually Transmitted Diseases, 37(9): 566-570.

Michels, C., Scales, H., Saunders, K.A., McGowan, S., Brombacher, F., Alexander, J.and Lawrence, E. 2009. Neither interleukin-4 receptor apha expression on CD4(+) T cells, or macrophages and neutrophils is required for protective immunity to Trichinella spiralis. Immunology, 128(1): e385-e394. [IIDMM][IIDRU]

Middelkoop, K., Bekker, L., Myer, L., Whitelaw, A.C., Grant, A., Kaplan, G., McIntyre, J.and Wood, R. 2010. Antiretroviral program associated with reduction in untreated prevalent tuberculosis in a South Africa township. AmericanJournal of Respiratory and Critical Care Medicine, 182: 1080-1085. [IIDMM]

Miles, D.J.C., Gadama, L. and Gumbi, A. 2010. Human immunodeficiency virus (HIV) infection during pregnancy induces CD4 T-cell differentiation and modulates responses to Bacille Calmette-Gurin (BCG) vaccine in HIV-uninfected infants. Immunology, 129: 446-454.

Millar, R.P. and Newton, C. 2010. The year in G-protein-coupled receptor research. Molecular Endocrinology, 24(1): 261-274.

Millar, R.P., Roseweir, A.K., Tello, J.A., Anderson, R.A., George, J.T., Morgan, K. andPawson, A.J. 2010. Kisspeptin antagonists: unraveling the role of kisspeptin in reproductive physiology. Brain Research, 1364: 81-89.

Minsaas, L., Planagumá, J., Madziva, M., Krakstad, B.F., Masià-Balagué, M., Katz, A.A.and Aragay, A.M. 2010. Filamin A binds to CCR2B and regulates its internalization. PLoS One, 5(8): e12212. doi: 10.1371/journal.pone.0012212. [IIDMM]

Mkhize, N., Gumbi, P., Liebenberg, L., Ren, Y., Smith, P.J., Denny, L.A. and Passmore, J.S. 2010. Persistence of genital tract T cell responses in HIV-infected women on highly active antiretroviral therapy. Journal of Virology, 84(20): 10765-10772. [IIDMM]

Mlotshwa, M., Riou, C., Chopera, D., de Assis Rosa, D., Ntale, R., Treunicht, F., Woodman, Z., Werner, L., van Loggerenberg, F., Mlisana, K., Abdool Karim, S., Williamson, C., Gray, C.M. and Caprisa 002 Study Team. 2010. Fluidity of HIV-1-specific T-cell responses during acute and early subtype C HIV-1 infection and associations with early disease progression. Journal of Virology, 84(22): 12018-12029. [IIDMM]

Morrow, B., Hsaio, N., Zampoli, M., Whitelaw, A.C. and Zar, H.J. 2010. Pneumocystis pneumonia in South African children with and without human immunodeficiency virus infection in the era of highly active antiretroviral therapy. PediatricInfectious Disease Journal, 29(6): 535-539.

Mowla, S., Pinnock, R., Leaner, V.D., Goding, C.R. and Prince, S. 2010. TPA-induced upregulation of TBX3 is mediated by AP-1 and contributes to breast cancer cell migration. Biochemistry Journal, 433: 145-153. [IIDMM]

Mulder, N.J. 2010. Protein domain architectures. Methods in MolecularBiology, 609: 83-95.

Mulder, N.J., Rabiu, H., Jamieson, G. and Vuppu, V. 2009. Comparative analysis of microbial genomes to study unique and expanded gene families in Mycobacterium tuberculosis. Infection Genetics and Evolution, 9(3): 314-321. [IIDMM]

Muller, E., Chirwa, T.F. and Lewis, D.A. 2010. Human papillomavirus (HPV) infection in heterosexual South African men attending sexual health services: associations between HPV and HIV serostatus. Sexually Transmitted Infections, 86: 175-180.

Nachega, J.B., Chaisson, R.E., Goliath, R., Efron, A., Chaudhary, M.A., Ram, M.,Morroni, C., Schoeman, H., Knowlton, A. and Maartens, G. 2010. Randomized controlled trial of trained patient-nominated treatment supporters providing partial directly observed antiretroviral therapy. AIDS, 24: 1273-1280.

Nicol, M.P. and Grobler, L.A. 2010. MVA-85A, a novel candidate booster vaccine for the prevention of tuberculosis in children and adults. Current Opinion in MolecularTherapeutics, 12(1): 124-134. [IIDMM]

Nortje, M. and Dunn, R.N. 2010. Spinal deformity in neurofibromatosis. SA Orthopedic Journal, 9(3): 31-34

Novitzky, N., Thomson, J., Thomas, V., Du Toit, C.E., Mohamed, Z. and McDonald, A.B. 2010. Combined submyeloablative and myeloablative dose intense melphalan results in satisfactory responses with acceptable toxicity in patients with multiple myeloma. Biology of Blood and Marrow Transplantation, 16(10): 1402-1410.

Ntusi, N., Aubin, L.A., Oliver, S.P., Whitelaw, A.C. and Mendelson, M. 2010. Guidelines for the optimal use of blood cultures. SAMJ South African Medical Journal, 100(12): 839-843.

Ntutela, S., Smith, P., Matika, L., Mukinda, J., Arendse, H.J., Allie, N., Estes, D.M., Mabusela, W., Folb, P.I., Steyn, L.M., Johnson, Q., Folk, W.R., Syce, J. and Jacobs, M. 2009. Efficacy of Artemisia afra phytotherapy in experiental tuberculosis. Tuberculosis, 89(1): S33-S40. [IIDMM]

Nunes, J.M., Riccio, M.E., Buhler, S., Di, D., Currat, M., Ries, F., Almada, A., Benhamamouch, S., Benitez, O., Canossi, A., Fadhlaoui-Zid, K., Fischer, G., Kervaire, B., Loiseau, P., de Oliveira, D.C.M., Papasteriades, C., Piancatelli, D., Rahal, M., Richard, L., Romero, M., Rousseau, J., Spiroski, M., Sulcebe, G., Middleton, D., Tiercy, J.M. and Sanchez-Mazas, A. 2010. Analysis of the HLA population data (AHPD) submitted tothe 15th International Histocompatibility/Immunogenetics Workshop by using the GENE[RATE] computer tools accommodating ambiguous data (AHPD project report). Tissue Antigens, 76(1): 18-30.

Odinsen, O., Parker, D., Radebe, F., Guness, M. and Lewis, D.A. 2009. Early detection of human immunodeficiency virus type 1-specific B-lymphocyte-derived antibodies in a high-risk population. Clinical and Vaccine Immunolgy, 16(7): 1060-1065.

Okpechi, I., Rayner, B.L., Van der Merwe, L., Mayosi, B.M., Adeyemo, A., Tiffin, N. andRamesar, R.S. 2010. Genetic variation at selected SNPs in the leptin gene and association of alleles with markers of kidney disease in a Xhosa population of South Africa. PLoS One, 5(2): e9086. [IIDMM]

Omar, F., Van Der Watt, G., November, V. and Pillay, T. 2010. Plasma free fatty acid reference interval in South African neonates in the first week of life. Annals ofClinical Biochemistry, 47: 381-382.

Opperman, D.J., Sewell, B.T., Litthauer, D., Isupov, M.N., Littlechild, J.A. and vanHeerden, E. 2010. Crystal structure of a thermostable Old Yellow Enzyme from Thermus scotoductus SA-01. Biochemical and Biophysical ResearchCommunications, 393: 426-431. [IIDMM]

Ortiz-Catedral, L., Kurenbach, B., Massaro, M., McInnes, K., Brunton, D.H., Hauber, M.E., Martin, D.P. and Varsani, A. 2010. A new isolate of beak and feather disease virus from endemic wild red-fronted parakeets (Cyanoramphus novaezelandiae) in New Zealand. Archives of Virology, 155: 613-620. [IIDMM]

Pandie, M., Sonderup, M., Meissner, P.N. and Mendelson, M. 2010. Acute porphyria precipitated by nevirapine. AIDS, 24(16): 2597-2599. [IIDMM]

Pandor, A., Ramesar, R.S. and Prince, S. 2010. Cell-specific differences in the processing of the R14W CAIV mutant associated with Retinitis Pigmentosa 17. Journalof Cellular Biochemistry, 111: 735-741. [IIDMM]

Parpia, Z.A., Elghanian, R., Nabatiyan, A., Hardie, D.R. and kelso, D.M. 2010. p24 antigen rapid test for diagnosis of acute pediatric HIV infection. JAIDS –Journalof Acquired Immune Deficiency Syndromes, 55(4): 413-419.

Pillay, S., Shephard, E.G., Meyers, A.E., Williamson, A.-L. and Rybicki, E.P. 2010. HIV-1 sub-type C chimaeric VLPs boost cellular immune responses in mice. Journal of Immune Based Therapies and Vaccines, 8(7): 1-6. [IIDMM]

Plantinga, T.S., Willment, J.A., O'Neill, L.A.J. and Brown, G.D. 2010. Genetic variation of innate immune genes inHIV-infected African patients with or without propharyngeal candidiasis. JAIDS – Journal of Acquired Immune Deficiency Syndromes, 55(1): 87-94

Potter, P.C., Kapp, A., Maurer, M., Guillet, G., Jian, A.M., Hauptmann, P. and Finlay, A.Y. 2009. Comparison of the efficacy of levocetirizine 5 mg and desloratadine 5 mg in chronic idiopathic urticaria patients. Allergy, 64(4): 596-604.

Prasanna, H., Sinha, D.P., Verma, A., Singh, M., Singh, B., Rai, M. and Martin, D.P. 2010. The population genomics of begomoviruses: global scale population structure and gene flow. Virology Journal, 7:20: 1-12. [IIDMM]

Ramaesh, T., Logie, J.J., Roseweir, A.K., Millar, R.P., Walker, B., Hadoke, P.W.F. andReynolds, R.M. 2010. Kisspeptin-10 inhibits angiogenesis in human placental vessels ex vivo and endothelial cells in vitro. Endocrinology, 151(12): 5927-5934.

Regnard, G., Halley-Stott, R.P., Tanzer, F.L., Hitzeroth, I.I. and Rybicki, E.P.2010. High level protein expression in plants through the use of a novel autonomously replicating geminivirus shuttle vector. Plant Biotechnology Journal, 8(1): 38-46. [IIDMM]

Reid, C. and Dunn, R.N. 2009. The surgical management of spinal tuberculosis in children and adolescents. SA Orthopedic Journal, 8(3): 56-62.

Riteau, N., Gasse, P., Fauconnier, L., Gombault, A. and Fick, L. 2010. Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and inflammation and fibrosis. American Journal of Respiratory and Critical Care Medicine, 182: 774-783.

Roberts, L., Passmore, J.S., Williamson, C., Little, F., Bebell, L.M., Mlisana, K., Burgers, W., van Loggerenberg, F., Walzl, G., Djoba Siawaya, J.F., Abdool Karim, Q. and AbdoolKarim, S. 2010. Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression. AIDS, 24: 819-831. [IIDMM]

Rogers, L.J., Wu, H.-T., Govender, D. and Denny, L.A. 2010. Case Study: Epithelioid sarcoma of the vulva. Southern African Journal of Gynaecological Oncology, 2(1): 30-32. [IIDMM]

Saathoff, E., Pritsch, M., Geldmacher, C., Hoffmann, O., Koehler, R.N., Maboko, L., Maganga, L., Geis, S., McCutchan, F.E., Kijak, G.H., Kim, J.H., Arroyo, M.A., Gerhardt, M., Tovanabutra, S., Robb, M.L., Williamson, C., Michael, N.L. and Hoelscher, M. 2010. Viral and host factors associated with the HIV-1 viral load setpoint in adults from Mbeya Region, Tanzania. JAIDS – JournalofAcquired Immune Deficiency Syndromes, 54(3): 324-331. [IIDMM]

Saglio, G., Kim, D.W., Issaragrisil, S., Le Coutre, P., Etienne, G., Lobo, C., Pasquini, R., Clark, R.E., Hochhaus, A., Hughes, T.P., Gallagher, N., Hoenekopp, A., Dong, M., Haque, A., Larson, R.A., Kantarjian, H.M. and Novitzky, N. 2010. Nilotinib versus Imatinib for newly diagnosed chronic myeloid leukemia. New England Journal of Medicine, 362(24): 2251-2259.

Samuel, C., Maistry, S., Meyer, E. and Whitelaw, A.C. 2010. Pneumocystis jirovecii infection of the external auditory canal. Southern African Journal of HIVMedicine, 38: 39-40.

Schafer, G., Guler, R., Murray, G., Brombacher, F. and Brown, G.D. 2009. The role of scavenger receptor B1 in infection with Mycobacterium tuberculosis in a murine model. PLoS One, 4(12): e8448. [IIDRU]

Secher, T., Vasseur, V., Poisson, D.M., Mitchelle, J.A., Cunha, F.Q., Alves-Filho, J.C.and Ryffel, B. 2009. Crucial role of TNF receptors 1 and 2 in the control of polymicrobial sepsis. Journal of Immunology, 182(12): 7855-7864.

Seimon, T.A., Kim, M.-J., Blumenthal, A., Koo, J., Ehrt, S., Wainwright, H.C., Bekker, L.,Kaplan, G., Nathan, C., Tabas, I. and Russell, D.G. 2010. Induction of ER stress in macrophages of tuberculosis granulomas. PLoS One, 5(9): doi:10.1371/journal.pone.0012772. [IIDMM]

Seoighe, C. and Gehring, C. 2010. Heritability in the efficiency of nonsense-mediated mRNA decay in humans. PLoS One, 5(7): e11657. doi:10.1371/journal.pone.0011657.

Shepherd, D.N., Martin, D.P., Van der Walt, E., Dent, K., Varsani, A. and Rybicki, E.P. 2010. Maize streak virus: an old and complex 'emerging' pathogen. Molecular Plant Pathology, 11: 1-12. [IIDMM]

Shey, M., Randhawa, A., Bowmaker, M., Smith, E., Scriba, T.J., de Kock, M., Mahomed, H., Hussey, G.D., Hawn, T. and Hanekom, W.A. 2010. Single nucleotide polymorphisms in toll-like receptor 6 are associated with altered lipopeptide- and mycobacteria-induced interleukin-6 secretion. Genes and Immunity, 11: 561-572. [IIDMM]

Sikakana, C.N.T. 2010. Supporting student-doctors from under-resourced educational backgrounds: an academic development programme. Medical Education, 44: 917-925.

Simon-Loriere, E., Martin, D.P., Weeks, K.M. and Negroni, M. 2010. RNA structures facilitate recombination-mediated gene swapping in HIV-1. Journal ofVirology, 84(24): 12675-1282. [IIDMM]

Sirugo, G., Williams, S.M., Royal, C., Newport, M.J., Hennig, B.J., Buonaguro, F., Velez Edwards, D., Ibrahim, M.E., Soodyall, H., Wonkam, A., Ramesar, R.S. and Rotimi, C.N. 2010. Report on the African Society of Human Genetics (AFSHG)Meeting, March 12-15 2009, Yaonde, Cameroon. American Journalof Tropical Medicine and Hygiene, 83(2): 226-229. [IIDMM]

Sissolak, G., Juritz, J.M., Sissolak, D., Wood, L. and Jacobs, P. 2010. Lymphoma – emergingrealities in sub-Saharan Africa. Transfusion and ApheresisScience, 42: 141-150.

Sissolak, G., Sissolak, D. and Jacobs, P. 2010. Human immunodeficiency and Hodgkin lymphoma. Transfusion and Apheresis Science, 42: 131-139.

Skeen, S., Lund, C., Kleintjes, S., Flisher, A.J. and MHaPP Research Programme Consortium. 2010. Meeting the Millennium Development Goals in Sub-Saharan Africa: what about mental health? International Review of Psychiatry, 22(6): 624-631.

Soares, A.P., Govender, L., Hughes, J., Mavakla, W., de Kock, M., Barnard, C., Pienaar, B., Janse van Rensburg, E., Jacobs, G., Stone, L., Abel, B., Scriba, T.J. and Hanekom, W.A. 2010. Novel application of Ki67 to quantify antigen-specific in vitro lymphoproliferation. Journal of Immunological Methods, 362: 43-50. [IIDMM]

Stupart, D.J., Goldberg, P.A., Levy, A. and Govender, D. 2009. Tuberculous anal fistulas-prevalence and clinical features in an endemic area. South African Journalof Surgery, 47: 116-118.

Teixeira, L., Guimiot, F., Dodé, C., Fallet-Bianco, C., Millar, R.P., Delezoide, A. andHardelin, J.P. 2010. Defective migration of neuroendocrine GnRH cells in human arrhinencephalic conditions. Journal of Clinical Investigation, 120(10): 3668-3672.

Tena-Coki, N., Scriba, T.J., Peteni, N., Eley, B.S., Wilkinson, R.J., Andersen, P.,Hanekom, W.A. and Kampmann, B. 2010. CD4 and CD8 T-Cell responses to mycobacterial antigens in African children. American Journal ofRespiratory and Critical Care Medicine, 182: 120-129. [IIDMM]

Tiffin, N., Meintjes, G., Ramesar, R.S., Bajic, V.B. and Rayner, B.L. 2010. Computational analysis of candidate disease genes and variants for salt-sensitive hypertension in indigenous Southern Africans. PLoS One, 5(9): e12989. [IIDMM]

Torgersen, E.B., Pharo, A., Haverson, K., Axelsen, A., Gaustad, P., Kotwal, G.J.,Sfyroera, G. and Mollnes, T.E. 2009. Inhibition of complement and CD14 attenuates the escherichia coli-induced inflammatory response in procine whole blood. Infection and Immunity, 77(2): 725-732.

Treurnicht, F., Seoighe, C., Martin, D.P., Wood, N., Abrahams, M., de Assis Rosa, D., Bredell, H., Woodman, Z., Hide, W., Mlisana, K., Abdool Karim, S.,Gray, C.M. and Williamson, C. 2010. Adaptive changes in HIV-1 subtype C proteins during early infection are driven bychanges in HLA-associated immune pressure. Virology, 396: 213-225. [IIDMM]

Uyttenhove, C., Brombacher, F. and Van Snick, J. 2010. TGF-B interactions with IL-1 family members trigger IL-4-independent IL-9 production by mouse CD4+T cells. European Journal of Immunology, 40: 2230-2235.[IIDMM] [IIDRU]

van Der Plas, H. and Hardie, D.R. 2010. Herpes simplex virus 1 and 2: a therapeutic approach. Southern African Journal of Epidemiology and Infection, 25(3): 5-9.

van der Walt, A., Lopata, A.L., Nieuwenhuizen, N. and Jeebhay, M.F. 2010. Work-related allergy and asthma in spice mill workers – theimpact of processing dried spices on IgE reactivity patterns. International Archives of Allergy and Immunology, 152: 271-278.

Van Der Watt, G., Owen, P., Berman, P., Meldau, S., Watermeyer, N.D., Olpin, S., Manning, N., Baumgarten, I., Leisegang, F. and Henderson, H.E. 2010. Glutaric aciduria type 1 in South Africa-high incidence of glutaryl-CoA dehydrogenase deficiency in black South Africans. Molecular Genetics and Metabolism, 101: 178-182.

Van Rooyen, J., Abratt, V.R., Belrhali, H. and Sewell, B.T. 2010. Crystallization of recombinant Bacteroides fragilis glutamine synthetase(GlnN)isolated using a novel and rapid purification protocol. Protein Expression and Purification, 74: 211-216. [IIDMM]

Vlok, A., Petersen, I., Dunn, R.N. and Stander, M. 2010. Shallow-water spinal injuries –devastatingbut preventable. SAMJ South African Medical Journal, 100: 682-684.

Vlok, I.J. and Dunn, R.N. 2010. Known primary with secondary disease: is tissue diagnosis necessary. SA Orthopedic Journal, 9(3): 35-36.

Wainwright, H.C. and Beighton, P. 2010. Dyssegmental dysplasia with bone entrapment and visceral ramifications. Pediatric and Developmental Pathology, 13: 46-49.

Wainwright, H.C. and Beighton, P. 2010. Lethal epiphyseal stippling in the foetus and neonate: pathological implications. Virchows Archiv, 456: 301-308.

Wainwright, H.C. and Beighton, P. 2010. Warfarin embryopathy: fetal manifestations. Virchows Archiv, 457: 735-739.

Walther, B., Miles, D.J.C. and Crozier, S. 2010. Placental malaria is associated with reduced early life weight development of affected children independent of low birth weight. Malaria Journal, 9(16): doi:10.1186/1475-2875-9-16.

Wan Ismail, W., King, J.A. and Pillay, T. 2009. Insulin resistance induced by antiretroviral drugs: current understanding of molecular mechanisms. Journal ofEndocrinology, Metabolism and diabetes of South Africa (JEMDSA), 14(3): 129-132.

Watermeyer, J., Kroger, W., O'Neill, H.G., Sewell, B.T. and Sturrock, E.D. 2010. Characterization of domain-selective inhibitor binding in angiotensin-converting enzyme using a novel derivative of lisinopril. Biochemical Journal, 428: 67-74. [IIDMM]

Wilkinson, D.E., Baylis, S.A., Padley, D., Heath, A.B., Ferguson, M., Pagliusi, S., Quint, W., Wheeler, C., Allan, B.R., Williamson, A.-L. andCollaborative Study Group. 2010. Establishment of the 1st World Health Organization international standards for human papillomavirus Type 16 DNA and Type 18 DNA. International Journal of Cancer, 126: 2969-2983. [IIDMM]

Williamson, D., Dent, K., Weber, B.W., Varsani, A., Frederick, J., Thuku, N., Cameron, R., van Heerden, J., Cowan, D. and Sewell, B.T. 2010. Structural and biochemical characterization of a nitrilase from the thermophilic bacterium, Geobacillus pallidus RAPc8. Applied Microbiology and Biotechnology, 88: 143-153. [IIDMM]

Wilmshurst, J., Lillis, S., Zhou, H., Pillay, K., Henderson, H.E., Kress, W., Muller, C.R., Ndondo, A., Cloke, V., Cullup, T., Bertini, E., Boennemann, C., Straub, V., Quinlivan, R., Dowling, J.J., Al-Sarraj, S., Treves, S., Abbs, S., Manzur, A.Y., Sewry, C.A., Muntoni, F.and Jungbluth, H. 2010. RYR1 Mutations are a common cause of congenital myopathies with central nuclei. Annals ofNeurology, 68(5): 717-726.

wolpaw, B.J., Mathews, C., Chopra, M., Hardie, D.R., Azevedo, V., Jennings, K. andLurie, M.N. 2010. The failure of routine rapid HIV testing: a case study of improving low sensitivity in the field. BMC Health Services Research, 10:73. http://www.biomedcentral.com/1472-6963/10/73.

Wonkam, A., Fieggen, K. and Ramesar, R.S. 2010. Beyond the Caster Semenya controversy. Journal of Genetic Counseling, 19(6): 545-548. [IIDMM]

Wonkam, A., Muna, W., Ramesar, R.S., Rotimi, C.N. and Newport, M.J. 2010. Capacity-building in human genetics for developing countries:initiatives and perspectives in Sub- Saharan Africa. Public Health Genomics, 13(7-8): 492-494. [IIDMM]

Wood, N., Bhattacharya, T., Keele, B.F., Giorgi, E.E., Liu, M., Gashen, B., Daniels, M., Ferrari, G., Haynes, B.F., McMichael, A.J., Shaw, G.M., Hahn, B.E., Korber, B.T.M. andSeoighe, C. 2009. HIV Evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC. PLoS Pathogens, 5(5): e1000414.

Woodcock, M., Mollan, S.P., Harrison, D., Taylor, D.A. and Lecuona, K. 2010. Mitomycin C in the treatment of a Schneiderian (inverted ) papilloma of the lacrimal sac. International Ophthalmology, 30: 303-305.

Woodward, J. and Sewell, B.T. 2010. Tomography of asymmetric bulk specimens imaged by scanning electron microscopy. Ultramicroscopy, 110: 170-175. [IIDMM]

Zar, H.J., Connell, T. and Nicol, M.P. 2010. Diagnosis of pulmonary tuberculosis in children new advances. Expert Review of Anti-infective Therapy, 8(3): 277-288. [IIDMM]

Zawaira, A., Gallotta, M., Beeton-Kempen, N., Coulson, L., Marais, P.C., Kuttel, M. andBlackburn, J. 2010. Exhaustive computational search of ionic-charge clusters that mediate interactions between mammalian cytochrome P450 (CYP) and P450-oxidoreductase (POR) proteins. Computational Biology and Chemistry, 34: 42-52. [IIDMM]

IIDMM – Institute of Infectious Disease and Molecular Medicine

OCRG – Medical Research Council/UCT Oesophageal Cancer Research Group

IIDRG – Medical Research Council/UCT Immunology of Infectious Diseases Research Unit

Patents

Kaschula, C.H., Hunter, R. andParker, M.I. 2010. Organosulfur compounds, a method of making organosulfur compounds and their use for inhibiting the growth of tumour cells. Registered in: South Africa. World Intellectual Property Organization. Date registered: 11/02/2010. WO 2010/016011 A1. [IIDMM][OCRG]


 

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